Paris Lalousis reviews a recent study that looks into the differences in brain connectivity between males and females, which suggests a potential sex-based divergence in the neurobiological underpinnings of psychiatric disorders.
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Anya Borissova summarises the therapeutic mechanisms of psilocybin in treatment-resistant depression and changes noticed in the amygdala and prefrontal cortex during emotional processing.
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Shubhangi Karmaker on a recent resting-state fMRI study that explores neural network disturbances that underpin the emergence of emotional symptoms in adolescent girls.
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Matthew Broome appraises a recent cohort study that looks at neural markers of resilience in young women at familial risk for major depressive disorder.
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This World Mental Health Day, we share a Wellcome Trust interview with Professor Andrew McIntosh, who has a £4.7 million award to explore why people develop depression. He tells Wellcome how he hopes his work will improve the lives of people with mental health conditions, and how he looks after his own mental wellbeing.
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Dan-Mikael Ellingsen explores the neurochemistry of placebo effects in major depression, as he reviews a recent study of the association between placebo-activated neural systems and antidepressant responses.
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For people who are suffering from a severe depression, antidepressants are a very effective treatment, but how they work is still not fully understood. The basic biochemistry of how one dose of the drug affects one part of the nervous system is known, e.g. increasing serotonin levels at the synapse by preventing it from being [read the full story…]
