Results: 11

For: cohort study AND cardiovascular disease

Patterns of inflammation in childhood and mental and cardiometabolic disorders in adulthood: mapping the trajectories

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Ruby Tsang summarises a recent longitudinal study of trajectories of inflammation in youth and risk of mental and cardiometabolic disorders in adulthood, which finds that high levels of inflammation in childhood may be linked to an increased risk of psychosis, depression and insulin resistance in early adulthood.

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Does a diagnosis of severe physical illness elevate suicide risk?

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Dona Matthews reviews a retrospective cohort study of 47 million people exploring the risk of suicide after diagnosis of severe physical illness, such as low-survival cancers, chronic ischaemic heart disease, chronic obstructive pulmonary disease, and degenerative neurological conditions such as Huntington’s disease.

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Depression and coronary heart disease: reasons to remain UPBEAT-UK

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Kirsten Lawson summarises the UPBEAT-UK programme of research into the relationship between coronary heart disease and depression and anxiety in primary care patients.

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The cardiovascular safety of dementia medications: a cross national study

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Two of the most widely available medicines for dementia in the UK are cholinesterase inhibitors and a N-methyl-D-aspartate (NMDA) receptor antagonists (NHS, 2013).  Both drugs are popular because they have been found to lead to improvements in dementia symptoms (Raina 2008). However, some have raised concerns about the safety for patients. These concerns are partly [read the full story…]

Daily psychological demands are associated with progression of carotid artery atherosclerosis

National Heart Month

As the British Heart Foundation National Heart Month draws to a close Lifestyle Elf and I were discussing their blog on heart attacks not being reduced in people taking vitamins and antioxidants which led to us to thinking about the relationship between stress and cardiovascular disease (CVD). Our colleagues in the Pittsburgh Health Heart Project [read the full story…]

People with schizophrenia are significantly more likely to die from heart disease and cancer

Unequal measures

Since starting this blog two years ago, I have written about a number of studies that highlight the health inequalities faced by people with severe mental illness. The evidence keeps piling up and it’s really quite shocking that we are not doing more to diagnose and treat physical health problems in people with conditions such [read the full story…]

The dose-response association between psychological distress and mortality, new BMJ meta-analysis shows the link

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There is an increasing body of evidence showing that depression and anxiety are linked with other health conditions like cancer and cardiovascular disease. I’ve blogged about the link between depression and stroke, and there are a number of other studies that show an association between psychological distress (the symptoms of depression and anxiety) and mortality, [read the full story…]

More evidence to suggest that central nervous stimulants are safe in the short-term for children and young people with ADHD

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Back in February, I blogged about a cohort study published in the New England Journal of Medicine, which concluded that ADHD drugs are not linked with an increased risk of serious cardiovascular events. The last few years has seen heated debate about the use of central nervous stimulants in children and young people. The lack [read the full story…]

ADHD drugs do not increase the risk of serious cardiovascular events, but long-term effects remain unknown

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A number of concerns have arisen over recent years about the safety of the various drugs used to treat ADHD (Attention Deficit Hyperactivity Disorder) in children and young adults. These central nervous system stimulants include methylphenidate, dexmethylphenidate, dextroamphetamines, amphetamine salts, atomoxetine and pemoline. Case reports have highlighted that sudden cardiac death can be brought on [read the full story…]

Middle-aged smokers with schizophrenia are significantly more likely to die from cardiac disease

Smoking man

We know from epidemiological studies that people with schizophrenia are 2-3 times more likely to smoke than the rest of the population.  We also know that schizophrenia is associated with a higher risk of coronary heart disease. This retrospective cohort study carried out by researchers from the University of Maryland set out to explore the impact [read the full story…]