Results: 12

For: randomised controlled trial AND systematic review

How do antiresorptive drugs affect the success of dental implants?

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Antiresorptive drugs, used to treat osteoporosis and metastatic bone disease, can complicate dental implant procedures by increasing the risk of medication-related osteonecrosis of the jaw (MRONJ). This systematic review investigates how these drugs affect the success and complications associated with osseointegrated dental implants. Key findings Antiresorptive drugs significantly increase the risk of (MRONJ), accounting for [read the full story…]

Can reducing loneliness help to alleviate or prevent anxiety or depression in young people? #ActiveIngredientsMH

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Anton Käll summarises a recent RCT of mindfulness training to reduce loneliness and increase social contact.

Ellie Pearce then shares her recent Wellcome Trust funded #ActiveIngredientsMH review, which looked into reducing loneliness as a potential active ingredient in both alleviating and preventing anxiety and depression in young people.

[read the full story...]

CBTp and medication in the treatment of psychosis: summarising the best evidence

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Clive Adams presents a summary of the latest evidence for CBTp and medication in the treatment of psychosis. This blog was published alongside Clive’s talk at the Understanding Psychosis and Schizophrenia conference in Bath on 11 June 2015

[read the full story...]

Reducing benzodiazepine prescribing in primary care

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Liz Hughes summarises two recent studies (1 systematic review and 1 RCT) that both investigate brief interventions for reducing the use of benzodiazepines in primary care.

[read the full story...]

Latest evidence from NICE on Obsessive Compulsive Disorder (OCD) and Body Dysmorphic Disorder (BDD)

Many of the drug treatments included in this report are not currently approved for use in the UK

Obsessive compulsive disorder (OCD) is a condition that has recently been given a significant amount of TV airplay and media coverage, perhaps most notably in the Channel 4 documentary Jon Richardson: A little bit OCD, which received mostly good reviews from mental health groups. Despite this reasonable public profile, our knowledge about the best way [read the full story…]

Do interventions proven to improve cardiovascular disease outcomes work for individuals with severe mental illness?

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Individuals with severe mental illness (SMI) have shortened life expectancies compared to the general population. This is partly down to higher rates of chronic physical illness. Cardiovascular disease (CVD) is the leading cause of death among patients using mental health services. It is assumed that interventions used to reduce CVD are similarly effective in patients with [read the full story…]

New evidence update from NICE on common mental disorders

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The NICE guideline on common mental disorders (PDF) was published back in May 2011, which means that it only included evidence published up until the end of 2010. This is a fast moving field, so NICE have now put out an evidence update, which focuses on new evidence published from Sept 2010 to Oct 2012. This [read the full story…]

NICE publish evidence update on generalised anxiety disorder in adults

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NHS Evidence have published an evidence update on generalised anxiety disorder in adults. Evidence updates are summaries of selected high quality evidence that has appeared since the relevant guideline was published, in this case NICE clinical guideline 113 ‘Generalised anxiety disorder and panic disorder (with or without agoraphobia) in adults: management in primary, secondary and community care’ [read the full story…]

Here is the evidence for exercising if you are depressed

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Ooh, what a palaver over the depression and exercise story!  Such a lot of words have been written about the study published in the BMJ last week, including by me. The study itself was well conducted but frankly disappointing (for us readers and the researchers themselves), finding as it did that a specific treatment to [read the full story…]

New evidence on delirium from NICE

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Around 20% of people on medical wards in hospital are affected by delirium. Sometimes called ‘acute confusional state’, delirium is a common clinical syndrome characterised by disturbed consciousness, cognitive function or perception, which has an acute onset and fluctuating course. NICE issued guidance on delirium in July 2010 and they have now published an evidence [read the full story…]