Thalia Eley and Gerome Breen explore a new systematic meta-review of predictors of antidepressant treatment outcome in depression, which looks at clinical and demographic variables, but also biomarkers including both genetic and neuroimaging data.
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Caroline Struthers summarises a recent population study that explores 10-year trajectories of depressive symptoms and subsequent risk of dementia.
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Eleanor Kennedy summarises a recent Cochrane systematic review, which finds no evidence to support the use of non-pharmacological interventions for depression in traumatic brain injury.
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John Baker summarises the findings of a recent review of people with schizophrenia, bipolar disorder and depression. The study looks at the adverse effects on physical health of psychotropic drugs (antipsychotics, antidepressants and mood stabilisers).
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Sally Adams summarises a recent meta-analysis of outcomes for independent and substance-induced disorders in people with depression and alcohol use disorders.
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Kirsten Lawson reports on a recent Cochrane systematic review, which highlights a lack of high quality trials about the efficacy and safety of antidepressants for depression in cancer.
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Natasha Clarke summarises a recent Cochrane review of pharmacotherapy for anxiety and comorbid alcohol use disorders, which found only very low quality evidence about the effectiveness of medication (buspirone, paroxetine, sertraline) for treating patients with both conditions.
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Dr Kirsten Lawson reviews one of Dr Wayne Katons’ last cohort studies looking into depression and diabetes and it’s effect on the risk of dementia.
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Although there have been huge advances in the treatment of heart disease, it is still the UK’s biggest killer (more information on heart disease can be found at the British Heart Foundation’s website). Depression after a heart attack is common (roughly 20% prevalence) and can worsen heart disease and increase the risk of death. A [read the full story…]
NICE published a clinical guideline on the treatment and management of depression in adults with chronic physical health problems in 2009. This new evidence update refreshes that guidance by searching for new systematic reviews and randomised controlled trials on the subject and summarising them in a short (16 page) document. The authors searched a range [read the full story…]
