Out in the woodland we are pleased that recent advances in medical care mean that more patients are surviving critical illnesses within intensive care units (ICU). “But what does that have to do with the Mental Elf?” I hear you say. Well, we Mental Elves are wondering whether this advancement in medical technology and technique are actually putting people [read the full story…]
Results: 125
For: medicinesKetamine for severe depression: what can we conclude from a small open label study?
Last week the media reported widely on a study of ketamine for depression (McShane et al, 2014). As usual the headlines made bold assertions, the Telegraph running with “Horse tranquilliser Ketamine could cure severe depression” (Knapton, 2014). But what did the paper authored by an Oxford group and published in the Journal of Psychopharmacology really [read the full story…]
Recommendations for commissioning quality weight management services
This guidance has been published and should be read alongside the Commissioning Policy A05 Complex and Specialised Obesity Surgery Services of the NHS Commissioning Board April 2013. It has been sponsored by the British Obesity and Metabolic Surgery Society, and is supported by a number of relevant professional bodies, including the Association of UK Dietitians [read the full story…]
US policy on prescription drug abuse: tackling an unique and significant problem
The fact that drug overdoses are the second largest cause of premature death from unintentional injuries in the US (for example, in 2010 there was 38,329 drug overdose deaths) is not a surprising statistic. What may surprise readers is that of these deaths 22,134 were attributed to prescription drugs. Indeed, almost one and a half [read the full story…]
Limited evidence for best antibiotic regimens to prevent postoperative infections after orthognathic surgery
Orthognathic surgery for the correction of dentofacial and craniofacial deformities has become a common a common procedure. Postoperative infection rates have been reported between 2-33%. The aim of this review was to provide evidence-based recommendations on the efficacy of different antibiotic regimens in preventing postoperative infections after orthognathic surgery Searches were conducted in Embase, Ovid [read the full story…]
Interventions for drug using offenders: What works in reducing drug use and criminal activity?
It is estimated that between 10% (Gunn 1991) and 39% (Brooke 1996) of prisoners in the UK are dependent on illicit drugs; and that 14.5% of male and 31% of female prisoners have serious mental health problems (Steadman 2009). Drug use can be associated with many health, social and criminological consequences; and when mental health [read the full story…]
Review finds only a small benefit from antibiotic use in patients with acute sinusitis
Sinusitis is one of the commonest reasons for visiting the doctor accounting for 15% to 21% of all adult outpatient antibiotic prescriptions. Patients may also present at dental practices, as pain from upper posterior teeth can be indistinguishable from sinusitis. Typical signs and symptoms are purulent nasal discharge, postnasal drip, sinus pain at palpation, nasal [read the full story…]
Currently insufficient evidence to decide if antibiotics are effective in treating irreversible pulpitis
Irreversible pulpitis often presents as an acute and intense pain and is a frequent reason for emergency dental visits. Treatment involves accessing the root canal of the tooth to remove the inflamed pulp (nerve) and cleaning the root canal. The aim of this review was to assess the effects of systemic antibiotics for irreversible pulpitis. [read the full story…]
D-cycloserine does not improve CBT for social anxiety disorder, but may accelerate early treatment gains
Clinical trials in the field of social anxiety to date have primarily focussed on the effect of either anxiolytic medication or cognitive behavioural therapy (CBT). At best these trials have demonstrated only moderate efficacy for either treatment independently (Davidson et al, 2004; Clark et al, 2003; Heimberg et al, 1998; Stein et al, 1998), and [read the full story…]
Largest RCT so far suggests that ketamine may be useful in the acute treatment of refractory depression
Major depression is a serious mental illness that often does not respond to mainstream drug treatment (antidepressants). In addition, there is usually a delay of 2-6 weeks before mood improves significantly. In situations like this, when at least two conventional antidepressants have been tried without success, depression is considered treatment-resistant. While multiple different strategies to [read the full story…]