This review of antibiotic prophylaxis during dental implant placement considered both systematic reviews and RCTs. Evidence from the 10 included RCTs suggests a small reduction (2%) in the risk of implant loss. These results are similar to a recent Cochrane review.
[read the full story...]
Helge Hasselmann summarises a new systematic review and meta-analysis, which confirms the antidepressant effects of ketamine.
[read the full story...]
This review update includes 23 new studies comparing the effects of antibiotic therapy adjunctive to scaling and root planning for periodontal disease. While some additional benefit was shown the authors could not establish definitive conclusions and guidelines regarding their use.
[read the full story...]
Should you use or prescribe rubefacients (creams and lotions that irritate the skin) to relieve musculoskeletal pain? We report on a new Cochrane systematic review that focuses on salicylate-containing rubefacients for acute and chronic musculoskeletal pain.
[read the full story...]
David Steele summarises a recent randomised controlled trial, which finds that (in the short-term) Lisdexamfetamine successfully decreased binge-eating behaviour in patients with binge-eating disorder. But can we trust this evidence?
[read the full story...]
Kathryn Walsh reports on a recent Cochrane systematic review of pharmacotherapies for cannabis dependence, which concludes that there is a lack of evidence for all medications reviewed.
[read the full story...]
Andrew Jones summarises a large Finnish population-based cohort study, which finds that childhood adversities strongly predict the use of psychotropic drugs (such as antidepressants and antipsychotics) in adulthood.
[read the full story...]
Helge Hasselmann reports on a new Cochrane systematic review of interventions for enhancing medication adherence, which finds insufficient evidence to draw any conclusions. The full health benefits of medicines will not be realised until better interventions and better studies are conducted in this area.
[read the full story...]
Elena Marcus summarises a recent network meta-analysis published in The Lancet of the comparative efficacy and tolerability of medication for the maintenance treatment of bipolar disorder.
[read the full story...]
Amy Green appraises a systematic review of CBT for insomnia (CBTi) in people with comorbid mental illness, which concludes that cognitive behaviour therapy could be an effective alternative to hypnotics. However, concerns about the review methodology cast some doubt on the findings.
[read the full story...]
