Eleanor Kennedy summarises a recent Cochrane review of pharmacotherapy for chronic cognitive impairment in traumatic brain injury, which finds insufficient evidence to support its use.
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Caroline Struthers reports on the findings of a follow-up paper of the DOMINO-AD trial, which compares Donepezil and Memantine for Moderate to Severe Alzheimer’s Disease, and looks at the effects these two drugs have on nursing home placement.
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John Baker summarises a recent Cochrane systematic review of psychosocial interventions for benzodiazepine harmful use, abuse or dependence.
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Rosalyn Nelson presents the latest Cochrane systematic review of Rivastigmine for Alzheimer’s disease, which brings together the results of 7 industry sponsored or funded trials, and concludes that Rivastigmine may be of benefit to people with Alzheimer’s disease.
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John Baker summarises the findings of a recent review of people with schizophrenia, bipolar disorder and depression. The study looks at the adverse effects on physical health of psychotropic drugs (antipsychotics, antidepressants and mood stabilisers).
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The update of a 2007 Cochrane review of parasympathomimetic drugs for dry mouth after radiotherapy did not identify an new studies. The 3 RCTs identified in the previous version provide limited evidence to support the use of pilocarpine hydrochloride in the treatment of radiation-induced xerostomia.
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Another new review of local or systemic azithromycin as an adjunct in non-surgical periodontal therapy includes 14 RCTs and demonstrates small benefits in periodontal parameters. However, the included studies are small and it is unclear if the benefits are clinically important.
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Lesley Dawson looks at a study, which asked whether intra-articular injection of corticosteroid leads to pain relief and increased function in people with osteoarthritis of the thumb, and how long any effects last.
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Dochka Hristova reports on a new Cochrane review of pharmacological interventions for self-harm in adults, which looks at the treatment effect on repetition of self-harm of antidepressants, antipsychotics, mood stabilisers and dietary supplements.
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In this blog, John Northfield considers a study of rates and patterns of prescribing psychotropic medications by GPs to people with learning disabilities and/or autism.
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