Results: 125

For: medicines

Weak evidence suggests small additional benefit from the use of local antimicrobials as adjunct to scaling and root planning for chronic periodontitis patients

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Scaling and root planning (SRP) is the main therapeutic approach to treating periodontitis. The adjunctive use of local antimicrobials has demonstrated some improvement in outcomes.  The aim of this review was to assess the effect on clinical outcomes of local antimicrobials as adjuncts to SRP, compared to SRP alone or plus placebo, in chronic periodontitis [read the full story…]

Scotland sees increase in prescribing rates for mental health drugs

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The Scottish Government have published their annual summary of prescribing statistics for mental health drugs. The report shows increases in the prescribing rates for all groups of drugs over the last 12 months. The prescribing costs of some groups of drugs have also risen (ADHD, dementia, depression) although other groups have seen a decline (insomnia [read the full story…]

Naltrexone as part of positive behavioural support appeared to have positive impact on self injurious behavour

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Self injurious behaviour in people with learning disabilities can have a major impact on quality of life, in addition to physical harm. Positive behaviour approaches have been showing some degree of success in supporting people with self injurious behaviour, and this case study investigated the possibility of combining pharmacological strategies with positive behaviour support plans. [read the full story…]

Clozapine use in women with borderline personality disorder and mild learning disability reduced rates of self injury and use of restraint

Medication

Clozapine is an atypical antipsychotic medication used to treat the symptoms of schizophrenia, most usually used as a treatment of last resort where people have not responded to other anti-psychotic treatments. It has a number of severe side effects including and can also cause the excessive production of saliva and weight gain.. The researchers in [read the full story…]

Should we use antibiotics to prevent complications from the removal of third molars?

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The use of antibiotics to prevent complications from the removal of third molars is a cause of debate. The aim of this review was to assess the efficacy of antibiotics in preventing infectious complications after third molar surgery What did they do The Medline Embase, ,and Cochrane databases were searched together with the references in [read the full story…]

Systemic antibiotics as an adjunct to non-surgical periodontal treatment

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Systemic and locally delivered antibiotics have been used as an adjunct to scaling and root planing (SRP) for the treatment of periodontal disease for many years. The aim of this review was to systematically evaluate the data concerning the effect of the concomitant administration of amoxicillin and metronidazole adjunctive to SRP in otherwise healthy adults. [read the full story…]

Limited benefit of slow release doxycycline gel as an adjunct to non-surgical periodontal maintenance treatment

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The aim of this study was to evaluate the efficacy of a slow release doxycycline gel (SRD) administered as an adjunct to non-surgical therapy in subjects with recurrent or persistent periodontitis but acceptable oral hygiene during supportive periodontal care. What did they do Patients suffering from persistent or recurrent moderate to severe periodontitis and undergoing [read the full story…]

Psychiatric drugs make up a bigger proportion of all prescription costs than they did a decade ago

Studies in which no placebo condition was included, resulted in a small but significant difference in favour of pharmacotherapy.

There continues to be a considerable amount of debate about the amount of psychiatric medication that is prescribed and how much it costs. Statistics from a number of countries have shown that many classes of drugs are being prescribed more and more, including antidepressants, antipsychotics and stimulants. Of course, as populations grow, people live longer [read the full story…]

Amoxycillin not helpful for acute sinusitis

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Acute sinusitis (rhinosinusitis) is a common disease with 1 in 5 antibiotic prescriptions for adults in the United States being for sinusitis.  US Centers for Disease Control  and Prevention (CDC) guidelines recommend using clinical criteria for diagnosis and  reserving antibiotic treatment for patients with moderately severe or severe symptoms.  The aim of this study was [read the full story…]

Psychiatric drugs are as effective as other drugs, says new review of meta-analyses

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There’s an interesting review in the British Journal of Psychiatry this week, which compares the effectiveness of psychiatric drugs with those used to treat physical health problems. The headline from the review is that ‘psychiatric drugs are as effective as other drugs’. Professor Stefan Leucht who led the review team claims that: There is a [read the full story…]