This review to assess the influence of two suture methods on the postoperative complications of lower third molar extraction included 5 RCTs . Findings suggest the use of secondary closure has a favourable effect on pain, facial swelling, and trismus but the quality of the evidence is limited.
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This review of the effectiveness of platelet-rich fibrin (PRF) in reducing postoperative complications of third molar surgery included 10 small RCTs suggesting that PRF may reduce but not prevent some complications.
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This review comparing the efficacy of Cox-2 inhibitors with ibuprofen after third molar removal included 12 RCTs suggesting that COX-2 inhibotors and Ibuprofen provide similar pain relief at 6, 8, and 12 h after third molar removal.
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This review of the prevalence of distal surface caries in second permanent molars associated with retained third molars included 11 mainly retrospective observational studies findins a pooled prevalence of 23% (95% CI; 2% to 44%).
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This review of coronectomy reoperation rates. included 15 studies with 14 being at high or medium risk of bias. The finding suggest a reoperation rate of 5.1%.
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This review of anaesthetic efficiency of articaine for lower third molar extraction included 9 RCTs ( 493 patients -770 lower molars). The findings suggest that 4% articaine with 1:100,000 epinephrine possesses superior anaesthetic efficiency relative to lidocaine.
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This review of the effectiveness of regenerative periodontal treatment for preventing periodontal defects following third molar surgery included 21 RCTs and suggested that these approaches were effective. However a majority of the included studies were at high risk of bias so the findings should be interpreted cautiously.
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This review of effectiveness of corticosteroids in the post-operative control of pain, swelling and trismus after third molar surgery included 17 RCTs suggesting that corticosteroid use had beneficial effects on pain swelling and trismus.
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16 observational studies were included in this review of the association between the presence of a lower third molar and the occurrence of a mandibular angle fracture in adults. The findings suggest that the odds of fracture are 3.16 (95%CI; 2.2- 4.54) higher in the presence of third molars
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6 studies were identified for this review of platelet-rich fibrin to improve outcomes after third molar extraction. The studies were small with contradictory findings so further high quality studies are needed.
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