Psychotropic medication during pregnancy: new umbrella review finds no convincing evidence of adverse health outcomes for the baby

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Flo Martin summarises a recent umbrella review which finds that we still have limited knowledge about the safety of psychotropic drug use in pregnancy.

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Tuberculosis and depression: multimorbidities are a global health challenge

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A team of experts from the Global NIHR Centre for IMPACT consider the findings of a recent meta review, which looks at the prevalence and risks of tuberculosis multimorbidity in low-income and middle-income countries.

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Serotonin hypothesis of depression: balance (and imbalance) is in the eye of the beholder

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The 2022 review by Moncrieff et al on the serotonin theory of depression received a great deal of media coverage. In this blog, Rebecca Wilkinson and Sameer Jauhar shed fresh light on this research and what it means for mental health science and practice.

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Is trauma a transdiagnostic risk for mental health problems? Recent umbrella meta-analysis suggests yes

Mental health services worldwide operate using discrete categories, but significant symptom overlap between different mental health disorders suggests that transdiagnostic approaches may be plausible.

In her debut blog, Megan Bailey summarises an umbrella review of systematic reviews and meta-analyses on whether psychological trauma can be considered as a transdiagnostic risk factor for mental health disorders.

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People with severe mental health difficulties are more likely to have poor dental health and dental disorders

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Masuma Pervin Mishu summarises an umbrella review on the prevalence of dental disorders among people with severe mental illness.

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Climate change and mental health: what do we know, and what don’t we know?

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Peter Coventry examines a big new umbrella review which signals the need for robust assessment and quantification of the mental health impacts of climate change.

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Power, equality, diversity and systemic change: the theory, barriers and enablers for patient and public involvement

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In her debut blog, Layla Mofrad summarises an umbrella review exploring the theory, barriers & enablers for patient and public involvement in health and social care research and service delivery.

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CBT reduces depressive symptoms in mothers with perinatal depression, but many questions remain unanswered

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In her debut blog, Kyla Vaillancourt summarises an umbrella review, which suggests that CBT is the most effective treatment for reducing symptoms of perinatal depression. However, many questions remain about psychological support for mothers, infants and families during the perinatal period.

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Youth mental health interventions: umbrella review presents efficacy and acceptability data

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In his debut blog, Nick Meader tackles a huge umbrella review of youth mental health interventions, which presents the efficacy and acceptability of 72 different approaches to help children and young people.

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Digital youth mental health interventions: will the evidence ever catch up?

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Robbie Fraser summarises an overview of systematic reviews, which finds that computerised CBT for anxiety and depression remains the best evidenced digital mental health intervention for young people.

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