What’s the relationship between stressful life events and psychosis?

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Kris Deering considers a 2-year prospective observational study published in the Lancet Psychiatry which found strong links between stressful life events and relapse in first-episode psychosis.

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Genetic risk for schizophrenia is associated with changes in heart structure and function

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Nadine Parker and Ole Andreassen summarise a recent UK population-based cohort study, which looks at the impact of polygenic risk for schizophrenia on cardiac structure and function in over 32,000 people.

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Mapping the trajectory of psychiatric diagnoses: Danish study finds that mental health diagnoses may change over time

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In her latest blog, Dona Matthews summarises a recent publication in The Lancet Psychiatry, which mapped the psychiatric diagnostic trajectories of 184,949 Danish patients over a 10-year period.

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Suicide and self-harm in children: prevalence rates cause for concern

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In Mahmoud Arif’s debut blog, he and Rasanat Fatima Nawaz summarise a meta-analysis published in The Lancet Psychiatry, which estimated the prevalence rates of self-harm behaviours and suicidal ideation in children aged 12 years and under.

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Are the kids alright? Emergency help for suicide and self-harm during the COVID-19 pandemic

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In her debut blog, Molly McCarthy appraises a recent Lancet Psychiatry systematic review and meta-analysis exploring the patterns of paediatric emergency department visits for suicide attempts, suicidal ideation, and self-harm incidents before and during the COVID-19 pandemic.

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Addressing premature mortality in mental illness: the “Gone Too Soon” framework

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Alvin Richards-Belle and Humma Andleeb review the Gone Too Soon framework, published yesterday in The Lancet Psychiatry, which suggests priorities for action to prevent premature mortality associated with mental illness and mental distress.

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Optimal antipsychotic dosing in first-episode schizophrenia: how much is too little, too much, or just right?

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Joe Pierre reports on the first published study exploring the relationship between antipsychotic dose and risk of relapse in first episode schizophrenia, which suggests that standard antipsychotic dosing is best for relapse prevention.

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If mental illness excludes us from the labour market, how can we make employment work for all?

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Ian Cummins reviews a Danish population-based cohort study, which finds that all mental health disorders were associated with shorter working life.

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Do different groups of people with schizophrenia respond differently to different antipsychotics?

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Murtada Alsaif considers a systematic review and meta-analysis published in the Lancet Psychiatry exploring the response of different subgroups of patients with schizophrenia to different antipsychotic drugs.

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Severe mental illness and comorbid chronic physical illness: the clock’s ticking

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In her debut blog, Jodie Ferris summarises a recent cohort study on the temporal relationship between severe mental illness diagnosis and chronic physical comorbidity in the UK, which contains important findings for care and future research.

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