Alternatives to medication for ‘treatment-resistant schizophrenia’

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Kalya Win Aung, Angela Kibia and Dorothy Williams consider a systematic review and network meta-analysis published by the Lancet Psychiatry on psychological and psychosocial interventions for treatment-resistant schizophrenia.

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Will this ADHD medication help my patient? Bridging the gap between efficacy and effectiveness

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Shuichi Suetani blogs a new study published today in The Lancet Psychiatry, which suggests that those patients who might benefit most from evidence-based guidance are the least represented in clinical trials about ADHD medication. Is it time to reconsider the value we place on RCTs when they do not include the vast majority of people who need help?

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Conversion practices: the PRIDE study explores harms experienced in the LGBTQIA+ community

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Vanessa Coeli summarises the PRIDE study on the experiences of conversion practices and mental health symptoms in sexual and gender minority adults in the US.

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Antidepressant discontinuation symptoms: what do the data really tell us?

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Gemma Lewis and Glyn Lewis summarise a robust systematic review and meta-analysis investigating the incidence of symptoms when discontinuing or withdrawing from antidepressants. The data suggest that 8-14% of patients will experience antidepressant discontinuation symptoms, and for around 2% these symptoms will be severe.

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Wide variance in the use of coercion in children and young people’s inpatient services

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John Baker reflects on a recent review on rates and risk factors of coercion in inpatient child and adolescent mental health services.

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Ethnic disparities in suicide mortality: what’s going on?

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Pauline Rivart summarises a national cohort study of ethnicity and suicide in England and Wales, which presents a “paradoxical finding of a lower rate of suicide in almost all minority ethnic groups compared with the White British majority”.

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What can GP records tell us about mental health throughout childhood?

Is the GP clinic the best form of support for young people experiencing recurrent mental health issues?

Niamh Dooley explores a retrospective study of ‘real-world’ data on young people’s use of general practitioners for mental health support.

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The great unknown? Assessing suicide risk in trials of psychological interventions for depression

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Derek de Beurs explores a meta-analysis which finds that randomised controlled trials of psychological interventions for depression rarely report assessments of suicide.

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Digitally augmented CBT for child anxiety is more efficient and no less effective than typical parent-led CBT

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Helen Dodd summarises a recent non-inferiority randomised controlled trial led by Cathy Creswell, which investigated the effectiveness of digitally augmented parent-led CBT for child anxiety.

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Community perinatal teams associated with more mental health service access and fewer postnatal relapses

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Roxanne Keynejad summarises the ESMI-II study on community perinatal mental health teams and mental health, obstetric and neonatal outcomes in pregnant women.

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