Aggressive challenging behaviour requires personalised interventions, robust caregiver relationships, and sustained system-level support

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James Smith summarises a rapid realist review of complex interventions for aggressive challenging behaviour in adults with intellectual disability.

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One size fits all: could transdiagnostic therapy treat mild anxiety and depression in preadolescents?

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Charlotte Huggett and Ian McGeoghegan blog about a case study, which looks at unifying treatment for mild anxiety and depression in preadolescence.

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Azithromycin as an adjunctive antibiotic in non-surgical periodontal therapy

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Another new review of local or systemic azithromycin as an adjunct in non-surgical periodontal therapy includes 14 RCTs and demonstrates small benefits in periodontal parameters. However, the included studies are small and it is unclear if the benefits are clinically important.

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No single systemic treatment was found to be effective for treatment of mouth ulcers

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The prevalence of mouth ulcers (recurrent aphthous stomatitis , RAS) has been estimated at between 5 – 60%. They can be painful and slow to heal.  There are three recognized forms; minor, major and herpetiform.  The peak age at onset is between 10 and 19 years of age but they can persist through adulthood. The [read the full story…]