The many faces of mental disorders

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Yuri Milaneschi discusses new research on the structure and presentation of mental health disorders, which suggests that although there are many different faces of major mental disorders, some of these faces are far more common than others.

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Antidepressant discontinuation symptoms: what do the data really tell us?

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Gemma Lewis and Glyn Lewis summarise a robust systematic review and meta-analysis investigating the incidence of symptoms when discontinuing or withdrawing from antidepressants. The data suggest that 8-14% of patients will experience antidepressant discontinuation symptoms, and for around 2% these symptoms will be severe.

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Thinking transdiagnostically about PTSD, depression and anxiety in US first responders

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Olga Lainidi summarises a network analysis exploring the interconnecting symptoms between PTSD, generalised anxiety disorder, and depression among First Responders based in the United States.

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Keep on movin’… Even small doses of physical activity can lower our risk of depression

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Elli Kypraiou considers a systematic review published in JAMA Psychiatry, which suggests that relatively small doses of physical activity were associated with substantially lower risks of depression.

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Adolescent depression is not the same as adult depression: new systematic review focuses on adolescents’ lived experiences

How are we currently supporting adolescents presenting with depression in clinical practice? Are we tailoring our approach, or are we treating them like mini adults?

Nina Higson-Sweeney reflects on the findings of a recent systematic review looking at the lived experience of adolescent depression, which has important implications for anyone supporting young people at risk of depression.

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Is it feasible to use apps to support people with first episode psychosis?

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In her debut blog, Rosa Pitts summarises the ARIES trial, which suggests it may be feasible to use a smartphone app (My Journey 3) to help prevent relapse in psychosis, although questions remain about long-term participant engagement with the app.

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Depression in young people: are we researching what matters most?

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Tamsin Ford asks what outcomes count, when it comes to measuring adolescent depression?

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Improving antidepressant outcomes: what works for whom and why?

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Thalia Eley and Gerome Breen explore a new systematic meta-review of predictors of antidepressant treatment outcome in depression, which looks at clinical and demographic variables, but also biomarkers including both genetic and neuroimaging data.

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The Lancet Psychiatry Commission on psychological treatments #SeeingFurther

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Ioana Cristea highlights some of the key ideas from the recently published Lancet Psychiatry Commission on psychological treatments research in tomorrow’s science. She also raises a number of objections to the 50-page report, which we hope will generate some much needed discussion on this topic.

Look out for our #SeeingFurther podcast with the authors of the Commission and a Twitter chat at 12:30pm GMT on Monday 19th March.

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Is mental malaise the psychological equivalent of obesity?

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Stan Kutcher reflects on a recently published briefing paper entitled: mental ill-health among children of the new century, which concluded that one in four 14 year old girls had self-reported “high symptoms of depression”.

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