This review of early versus delayed initiation of space closure after tooth extraction on the rate of orthodontic tooth movement included 11 RCTs. The findings suggest little difference between the two approaches but the included studies are small and none of the theam are at low risk of bias.
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This review of the the effects and sequela of early extraction of first permanent molars included 11 observational studies providing limited quality evidence of the consequences of early extraction. High quality prospective studies are needed.
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8 small studies were included in this review comparing en masse retraction and two-step retraction for orthodontic space closure. While both were effective the en masse/miniscrew combination demonstrated a small statistically significant benefit in terms of incisor retraction and anchorage preservation.
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4 RCTs were included in this review of Nickel- titanium closing springs (NiTi-CS) and elastomeric power chains (EPC). The findings suggest there is medium quality evidence that space closure is faster with NiTi-CS.
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