This review evaluating the preventive effect of regular applications of fluoride varnish (FV) on the development of white spot lesions (WSL) during orthodontic treatment included 7 RCTs. Meta-analyses demonstrated a reduction in the risk of WSL with regular FV applications but the certainty of evidence was very low.
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This review of the caries preventive effectiveness of topical fluorides in the primary dentition included 24 RCTs with 10 RCTs contributing to a network meta-analysis (NMA). While the NMA did allow a ranking of effectiveness the number of studies involved was small and 17 of the 24 studies were considered to be at high risk of bias.
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This Cochrane review asessing interventions with pregnant women, new mothers or other primary caregivers of infants in the first year of life for preventing early childhood caries included 17 RCTs .
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This review of self-applied topical fluorides for the prevention reversal of enamel white spot lesions during fixed orthodontic treatment included 3 RCTs two of which were at high risk of bias.
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This review of treatments used to treat dentine hypersensitivity. 254 different agents were tested with all showing some effectiveness in short term.
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This evidence-based clinical practice guideline on the non-restorative treatments for carious lesions in primary and permanent teeth from the American Dental Association provides 11 recommendations.
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Ten studies involving a total of 394 patients were included in this review of desensitising agents during tooth bleaching. While the results suggest a reduction in sensitivity variation in the concentration of the agents used, the quality of the included studies means the results should be interpreted with caution.
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This review of mouthwash use in patients having fixed banded orthodontic treatment included 15 small studies and suggests that they reduce plaque levels. However the clinical relevance of the findings are uncertain and larger well conducted studies are needed.
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