This review of the efficacy of topical sialogogue spray containing malic acid 1% for treating xerostomia included 5 RCTs involving 244 patients. While the findings suggested a benefit the available studies are small, of short duration and none are at low risk of bias.
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The use of topical fluoride together with fluoridated water and fissure sealants are mainstays of caries management. A range of non-fluoride agents caries preventive agents are also in use and these are reviewed to provide evidence-based clinical recommendations. The authors evaluated studies of sucrose-free polyol chewing gums, xylitol dentifrices, chlorhexidine, chlorhexidine in combination with thymol, [read the full story…]
