While most people would likely associate tricyclic antidepressants (TCAs) with more common adverse effects such as dry mouth, sedation and constipation, there is some evidence to suggest increased occurrence of bone fractures (Vestergaard, Rejnmark, & Mosekilde, 2006). However, the topic remains controversial and conflicting results about the association of TCAs and fracture risk abound (e.g. [read the full story…]
Bipolar disorder is considered a hereditary condition. There is emerging evidence that prodromes/early symptoms are evident in children before disorders develop. This potentially offers a chance to treat and prevent the development of mental health problems in adulthood. Being able to identifying early symptoms of the onset of this mental health disorder is clearly important, however, [read the full story…]
The prevalence of autistic spectrum disorders has risen dramatically in the last thirty years, with recent estimates suggesting that 1 in 88 children in the United States have an autistic spectrum disorder. This increasing prevalence could simply be due to changes in the diagnosis of such disorders and so be of little interest. However, there [read the full story…]
Cystic fibrosis (CF) is a genetic disorder that leads to the overproduction and accumulation of mucus in the lungs, which can result in airway obstruction and life-threatening bacterial. Four risk factors related to CF are considered to increase the risk of dental caries; a 20- fold increase in intraoral Streptococcus mutans levels; gastroesophageal reflux disease [read the full story…]
The risks of congenital malformations and impact of cognitive development after foetal exposure to anti-epileptic drugs has been known for some time. Sodium valproate is a frequently used drug for epilepsy and other disorders (including bipolar disorder and migraine). The researchers aimed to examine the link between foetal exposure and subsequent development of autism. Methods [read the full story…]
The potential dangers of illegal drug use are never far from the media spotlight, and drug use during pregnancy may be associated with particular health problems both for the Mother and baby. Drug use during pregnancy has been linked with a number of negative outcomes, for example, cocaine use has been linked with an increased [read the full story…]
One of the first lectures I attended at Medical School was an introduction to the “nature vs. nurture” debate. I recall the general consensus was a bit of both, however it wasn’t until many years later and well into my public health career that I began to see the value of this perspective in improving [read the full story…]
Alcohol, together with tobacco and obesity, is one of the most important modifiable causes of morbidity and premature mortality, and is estimated to account for around 4% of deaths worldwide. This study attempted to clarify the number of alcohol-attributable cancer deaths in the United States, and the years of potential life lost in this way. [read the full story…]
Two of the most widely available medicines for dementia in the UK are cholinesterase inhibitors and a N-methyl-D-aspartate (NMDA) receptor antagonists (NHS, 2013). Both drugs are popular because they have been found to lead to improvements in dementia symptoms (Raina 2008). However, some have raised concerns about the safety for patients. These concerns are partly [read the full story…]
The symptoms of mild cognitive impairment (MCI) include problems with cognitive functioning such as day-to-day memory. In some individuals it is the first sign of dementia, whereas in others it may be due to resolvable factors such as being the side-effect of medication (Alzheimer’s Society, 2012). At present it is unclear how many people with [read the full story…]
