12 RCTs were included in this Cochrane review update of surgical approches for the management of oral and pharyngeal cancer. The certaintly of the evidence was very low as there were limited numbers of studies for each comparison.
[read the full story...]Limited evidence suggests that co-morbid chronic physical illness may not increase risk for recurrence in depression
There is a widespread clinical presumption that people who have both major depressive disorder (MDD) and a co-morbid chronic physical illness represent a ‘double trouble’ group. This leads to the expectation that the depression prognosis for these people would be poor with increasing likelihood of recurrence. Evidence supports the view that depression is prevalent among [read the full story…]
Cochrane review cannot support training to recognise early signs of recurrence in schizophrenia due to low quality evidence
NICE Guidelines state that around three quarters of people with a diagnosis of schizophrenia experience a chronic illness: with recurrent episodes of remission and relapse. One way that chronic physical health conditions, such as diabetes and heart disease, are managed is by using early warning signs (EWS) training and this prevention strategy is now often [read the full story…]
keratocystic odontogenic tumour recurrence rates
The keratocystic odontogenic tumour (KCOT, odontogenic keratocyst (OKC)) was first described in the literature in 1956 and is classified by the World Health Organization classified as a benign odontogenic tumour. It is generally accepted that they arise from the remnants of the dental lamina and are benign but locally aggressive and tend to reoccur. They [read the full story…]