Psilocybin for ‘treatment-resistant depression’: an island of hope in an ocean of uncertainty?

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In this blog, UCL MSc students consider an RCT published in the New England Journal of Medicine, which suggests that psilocybin-assisted psychotherapy may help reduce depression in people with severe and enduring illness, but side effects are common and more research is needed to look into longer term effects.

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Promising scalable brief psychological programme to improve refugee youth mental health

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Katie McQuillan reviews a recent randomised controlled trial which suggests that a brief community programme may help improve youth and caregiver psychological wellbeing in young Syrian refugees settled in Jordan.

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Virtual reality therapy for psychosis: positive patient experiences and few side effects

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Steven Parkes considers a randomised controlled trial exploring the satisfaction and side effects of gameChange, a virtual reality intervention targeting anxiety in every day situations for patients with psychosis.

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Does what you eat affect how you feel?

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Daisy Crick summarises a recent paper on the casual relationship between polyunsaturated fatty acids and depression.

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Psychedelics-assisted psychotherapy for alcohol use disorder: room for more evidence

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In her debut blog, Heidi Stevens reviews a recent US randomised controlled trial on psilocybin-assisted psychotherapy for adults with alcohol use disorder, which leaves us with more questions than answers.

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Equipping young adolescents with wellbeing skills: does a universal, classroom-based CBT intervention promote positive mental health?

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Emily Hards and Maria Loades summarise a cluster randomised controlled trial exploring the effectiveness of universal process-based CBT for positive mental health in early adolescence.

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Ketamine and suicidal ideation: French trial finds modest short-term effects

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Anya Borissova reviews a French trial that claims to be evidence that “ketamine is rapid, safe in the short term, and has persistent benefits for acute care in suicidal patients”.

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Can social recovery therapy improve social disability in young people?

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In her debut blog, Jude Madani summarises the findings of the PRODIGY trial, which looked at the clinical and cost-effectiveness of social recovery therapy for the prevention and treatment of long-term social disability among young people with emerging severe mental illness.

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Acceptance and commitment therapy for early psychosis: results from the INTERACT trial

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Silke Vereeken summarises the INTERACT randomised controlled trial, which reports on the efficacy of Acceptance and Commitment Therapy in daily life for people with early psychosis.

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Intensive home treatment in crisis: a randomised controlled trial from the Netherlands

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Lucy Maconick and Sonia Johnson appraise a recent trial conducted in Amsterdam, which finds that intensive home treatment substantially reduces the use of hospital beds in acute psychiatry, without compromising patient safety.

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