Is gabapentin a promising drug for the treatment of alcohol dependence?

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Alcohol misuse is responsible for about 4% of all deaths annually, and in the UK it costs the NHS more than £3 billion per year.  A number of medications are currently licensed for the treatment of alcohol dependence. Unfortunately the medications don’t work for everyone and in the USA at least, fewer than 10% of [read the full story…]

‘Beating the Blues’ intervention shows promise for reducing depression and improving quality of life in older African Americans

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This paper reports the findings of a study exploring a new approach to treating the symptoms of depression in older African Americans. This a group of the population with very high levels of general health care needs – the result of a combination of factors including the USA’s political and social history but also modern [read the full story…]

If I pay you, will you have your injection?

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Getting patients to take their medication as prescribed is notoriously difficult. Regardless of condition only about 50% of patients adhere to prescribed regimes. This is particularly the case in chronic or complex conditions worldwide and improving this problem has the potential to save considerable health burden and costs. Adherence in mental health is no different. [read the full story…]

Seeing is believing; how does family presence during cardiopulmonary resuscitation affect psychological outcomes for family members?

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There are around 60,000 out-of-hospital cardiac arrests in the UK every year. Some of these events occur in the presence of relatives who may witness the cardiopulmonary resuscitation (CPR) by the resuscitation team (you can find out more about CPR at the Resuscitation Council’s website). The emotional consequences of this for the relatives and the [read the full story…]

The CHAMP RCT finds that CBT is more effective than standard care for reducing health anxiety

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Cognitive behavioural therapy (CBT) is substantially more effective than standard care at reducing symptoms of health anxiety in medical patients, and can be delivered by non-specialist staff with minimal training at little extra cost, according to an RCT published by The Lancet today. The CHAMP (Cognitive behaviour therapy for Health Anxiety in Medical Patients) trial [read the full story…]

Using adaptive treatments for smoking cessation may prove effective

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Around 20% of adults in the UK smoke cigarettes regularly. Smoking was the primary cause of approximately 462,900 hospital admissions and 79,100 (18%) deaths in adults over the age of 35 last year. Therefore, smoking cessation represents a serious (and costly!) clinical challenge on an individual and global level. Many smoking cessation aids are available, [read the full story…]

Concurrent treatments may be effective in treating comorbid alcohol dependence and PTSD

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In those with post-traumatic stress disorder (PTSD), alcohol abuse or dependence is the most common co-morbid disorder. Unfortunately, although individuals with PTSD and alcohol dependence (AD) often have complex needs, the treatments available usually only target one issue. This is often due to specialist treatment services not having access to treatments for comorbid disorders, and [read the full story…]

Systematic review of dropout rates from clinical trials of methylphenidate for adult ADHD

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Attention deficit hyperactivity disorder (ADHD) is characterised by inattention, excessive activity levels and impulsive behaviours. Although it is an early developmental condition and is associated with childhood, in many instances, it is a lifelong condition. ADHD in adulthood is increasingly being recognised. Clinical guidelines and research suggest that the stimulant drug methylphenidate can reduce ADHD [read the full story…]

Latest evidence from NICE on Obsessive Compulsive Disorder (OCD) and Body Dysmorphic Disorder (BDD)

Many of the drug treatments included in this report are not currently approved for use in the UK

Obsessive compulsive disorder (OCD) is a condition that has recently been given a significant amount of TV airplay and media coverage, perhaps most notably in the Channel 4 documentary Jon Richardson: A little bit OCD, which received mostly good reviews from mental health groups. Despite this reasonable public profile, our knowledge about the best way [read the full story…]

CBT may prevent depression in at-risk children whose parents have a history of depression

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The harmful impact of depression extends far beyond the individual sufferer to caregivers, friends and family members.  Children of people with depression are more likely to suffer from depression themselves.  This may be due to both inherited and environmental factors. This new randomised controlled trial (RCT), published earlier this week in JAMA Psychiatry, set out [read the full story…]