Concurrent treatments may be effective in treating comorbid alcohol dependence and PTSD

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In those with post-traumatic stress disorder (PTSD), alcohol abuse or dependence is the most common co-morbid disorder. Unfortunately, although individuals with PTSD and alcohol dependence (AD) often have complex needs, the treatments available usually only target one issue. This is often due to specialist treatment services not having access to treatments for comorbid disorders, and [read the full story…]

Systematic review of dropout rates from clinical trials of methylphenidate for adult ADHD

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Attention deficit hyperactivity disorder (ADHD) is characterised by inattention, excessive activity levels and impulsive behaviours. Although it is an early developmental condition and is associated with childhood, in many instances, it is a lifelong condition. ADHD in adulthood is increasingly being recognised. Clinical guidelines and research suggest that the stimulant drug methylphenidate can reduce ADHD [read the full story…]

Latest evidence from NICE on Obsessive Compulsive Disorder (OCD) and Body Dysmorphic Disorder (BDD)

Many of the drug treatments included in this report are not currently approved for use in the UK

Obsessive compulsive disorder (OCD) is a condition that has recently been given a significant amount of TV airplay and media coverage, perhaps most notably in the Channel 4 documentary Jon Richardson: A little bit OCD, which received mostly good reviews from mental health groups. Despite this reasonable public profile, our knowledge about the best way [read the full story…]

CBT may prevent depression in at-risk children whose parents have a history of depression

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The harmful impact of depression extends far beyond the individual sufferer to caregivers, friends and family members.  Children of people with depression are more likely to suffer from depression themselves.  This may be due to both inherited and environmental factors. This new randomised controlled trial (RCT), published earlier this week in JAMA Psychiatry, set out [read the full story…]

Can assessing and acting on quality of life scores improve patient satisfaction? New study concludes yes, but the results actually say no

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For mental health patients, quality of life (QoL) can include many things like self-esteem, autonomy, satisfaction with the care they’re receiving and the staff who are caring from them, reduced symptoms, minimal side-effects from treatment and good overall functioning. Measuring QoL can pick up on difficulties a patient is having that wouldn’t have otherwise come [read the full story…]

Can brain imaging help predict who will respond to CBT versus antidepressants?

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A major challenge in the treatment of depression is that only a proportion of people respond to the first treatment they try.  For example, with antidepressants only 40% of people will see their symptoms fall to a level that can be considered a recovery.  Trying further treatments after the first one does not work can [read the full story…]

Group-based CBT effective in improving anger control by people with learning disabilities

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Cognitive behavioural therapy (CBT) is an approach used to help people manage problems by changing the way they think and behave. It is a talking therapy designed to help examine they way in which their actions can affect they way they think and feel. It looks for practical ways to improve states of mind on [read the full story…]

Treatment of depression after a heart attack does not improve the long-term risk of adverse cardiac events but may increase survival

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Although there have been huge advances in the treatment of heart disease, it is still the UK’s biggest killer (more information on heart disease can be found at the British Heart Foundation’s website). Depression after a heart attack is common (roughly 20% prevalence) and can worsen heart disease and increase the risk of death.  A [read the full story…]

Talking therapy for teenagers (MBT-A) reduces self-harm and depression in self harming teens over a 12 month period

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In adults there is a growing body of evidence for psychotherapeutic interventions such as Transference Focussed Psychotherapy, Mentalization-Based Treatment and Dialectic Behavioural Therapy for patients who self harm. In the teenage population, there has been limited evidence to show that interventions are better than the treatment already provided. MBT has developed from psychodynamic psychotherapy and [read the full story…]

Moderate intensity exercise programmes do not improve depressive symptoms in elderly care home residents: results from the OPERA trial

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Depression is a common problem in older adults with some data suggesting significant symptoms are present in over 40% of nursing home residents (Teresi, 2001). Clearly physical exercise has a number of benefits particularly with regards to cardiovascular health. Some of you may remember the Mental Elf blog back in September 2012 with positive results from [read the full story…]