When we think of Parkinson’s disease (PD), hallucinations and delusions are probably not the first symptoms that come to mind. And yet, it is estimated that nearly half of all patients with PD experience psychotic symptoms at one time or another. Although deficits in motor function are seen as the hallmark of PD, it is [read the full story…]
Ketamine for severe depression: what can we conclude from a small open label study?
Last week the media reported widely on a study of ketamine for depression (McShane et al, 2014). As usual the headlines made bold assertions, the Telegraph running with “Horse tranquilliser Ketamine could cure severe depression” (Knapton, 2014). But what did the paper authored by an Oxford group and published in the Journal of Psychopharmacology really [read the full story…]
The dark side of universal prevention: Limited effectiveness and harmful effects of classroom-based CBT in preventing adolescent depression
Depression is a common problem in adolescence, with statistics showing that around 20% of young people will go through at least one clinically depressive episode by the age of 18 years. Given the significant impairment and deleterious consequences of depression, sustained efforts have been dedicated to preventive and early intervention. In a recent large trial [read the full story…]
Extended therapy with varenicline reduces rates of smoking relapse in people with serious mental health issues
People with serious mental health issues such as schizophrenia have higher rates of cigarette smoking than the general population, with estimates suggesting more than 50% are current smokers. When people in this population do manage to quit during treatment we then see particularly high rates of relapse after treatment ends. A new randomised control trial (Evins [read the full story…]
Combination of treatments may improve smoking cessation
Smoking is a major cause of morbidity and mortality across the world and accounts for over 60% of deaths in people who do smoke. The World Health Organisation estimates that tobacco kills almost 6 million people per year, with 5 million as a result of direct tobacco use. Innovative treatment approaches aimed at improving smoking [read the full story…]
Pilot study suggests that CBT may be a viable alternative to antipsychotics for people with schizophrenia, or does it?
People with schizophrenia stop taking their antipsychotics for a wide range of reasons (e.g. debilitating side effects or a belief that they will not help them), but when they do health professionals often find it extremely difficult to care for these patients, because the alternative treatment options available to them are very limited. Of course, [read the full story…]
Targeted mental health support can improve borderline-clinical behavioural problems in children
The statistic that one in four adults in Britain will experience a mental health problem in any given year is well known (if still debated), but a recent report by the Children and Young People’s Mental Health Coalition revealed a lack of such statistics for children. The report also highlighted that Office for National Statistics [read the full story…]
Focal psychodynamic therapy or CBT vs optimised treatment as usual in outpatients with anorexia
Anorexia nervosa has long been known to have a poor prognosis and few effective treatments are available (Kaplan and Garfinkel, 1999). Research in this area is limited, particularly in regards to evidence-based guidance. The NICE eating disorders guidance (2004) is in need of an update, although there is a more recently produced care pathway. Other [read the full story…]
Long term maintenance treatment with antipsychotics: a cautionary note from recent research
The support of individuals with experience of psychosis is complex and relies on a combination of psychopharmacology (antipsychotic drugs), psychological therapies and social interventions. Antipsychotics will often be the first line treatment offered, with the intention of reducing psychotic symptom burden. Following the resolution of immediate symptoms the role of antipsychotics becomes less clear; should [read the full story…]
RCT compares two different versions of enhanced cognitive behavioural therapy for anorexia nervosa in an inpatient setting
A general misconception about anorexia is that it’s just about eating and ‘being thin’, but it’s more complex than that. The illness affects multiple aspects of a person’s life, and often goes hand in hand with other psychological issues such as low mood, or excessive worry. In addition, the jury is still out on the exact [read the full story…]