Lisdexamfetamine for binge-eating disorder

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David Steele summarises a recent randomised controlled trial, which finds that (in the short-term) Lisdexamfetamine successfully decreased binge-eating behaviour in patients with binge-eating disorder. But can we trust this evidence?

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Engaging inpatients with mental health rehabilitation activities

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Elly O’Brien reports on a recent RCT of a staff training intervention for inpatients in mental health rehabilitation, which is designed to increase patients’ engagement in activities.

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Brief interventions for substance misuse in primary care

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Claire Mokrysz reports on two RCTs in JAMA that find no superiority over control for brief interventions for substance misuse in primary care. A finding that casts some doubt on interventions such as motivational interviewing for unhealthy drug use in primary care patients.

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Folic acid for depression: results of the FolATED study

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Susie Johnson reports on the FolATED RCT and economic evaluation of folic acid for depression. The study finds no evidence that folic acid is clinically effective or cost-effective in augmenting antidepressants and speculates instead that methylfolate may be a better candidate for future research.

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Mindfulness Based Stress Reduction programmes reduced stress in mothers of children with disabilities in community sample RCT

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Mindfulness is increasingly recognised as an effective way to reduce stress and improve well-being

Here Kate van Dooren looks at a randomised controlled trial of a mindfulness based stress reduction programme with mothers of children with autism and other developmental delays to look at its impact on levels of distress over time.

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Relationship training for children and family practitioners: does it work?

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Martin Webber looks at a rare social work randomised controlled trial (RCT) on relationship training for practitioners working with children and families and finds that even findings from a study using ‘gold standard’ research methodology have to be carefully examined for reliability.

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Folic acid for depression: RCT finds no effect on reducing incidence of depression or bipolar

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Elly O’Brien summarises a recent RCT of folic acid for depression, which explores whether mood disorders can be prevented in young people at familial risk. The trial finds no evidence that folic acid supplementation reduces the incidence of mood disorders compared to those taking placebo.

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Sustained smoking cessation intervention for hospitalised smokers

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Sally Adams summarises a new randomised controlled trial in JAMA, which tests a sustained care intervention and post-discharge smoking cessation for hospitalised smokers.

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Improving mental health literacy in the classroom: new HeadStrong RCT

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Lisa Burscheidt reports on an RCT of the Headspace mental health literacy intervention and the impact it has on the mental health literacy, stigma, help-seeking and mental health of a group of young people in Australia.

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Depression and cancer: Lancet papers on prevalence and integrated collaborative care

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Kirsten Lawson highlights a trio of Lancet papers on the prevalence of depression in cancer patients and the efficacy of a new treatment programme called ‘Depression Care for People with Cancer’.

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