Caroline Struthers reports on the findings of a follow-up paper of the DOMINO-AD trial, which compares Donepezil and Memantine for Moderate to Severe Alzheimer’s Disease, and looks at the effects these two drugs have on nursing home placement.
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Paul Ramchandani considers an RCT of treatment for childhood anxiety disorder in the context of maternal anxiety disorder, which finds that mother-child interaction might be of value for childhood anxiety disorder.
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Rosalyn Nelson presents the findings of a small RCT of Pivotal Response Treatment groups for parents of children with autism, which has promising results in terms of encouraging children to communicate.
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Clarissa Giebel highlights a recent RCT, which concludes that antipsychotic use by people with dementia in nursing homes can be effectively reduced through the use of a review protocol, which includes regular scrutiny of prescriptions and targeted education for physicians and nurses.
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Raphael Underwood presents the 3 year follow up of the OCTET trial of community treatment orders for people with psychosis, which finds no significant difference on readmission or disengagement for patients on CTOs compared to those discharged to voluntary status via Section 17 leave.
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Emily Stapley summarises a recent RCT of a cognitive behavioural prevention programme for young people at risk of depression.
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Another debut blog today, this time from Suzanne Dash, who presents the results of the REEACT trial published last week in the BMJ. The study found limited uptake of computerised CBT by people with clinical depression and no benefit of free or commercially available cCBT packages over usual GP care.
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Kirsten Lawson explores the benefits of working across professional and therapeutic boundaries, highlighted beautifully by the recent COINCIDE RCT of collaborative care for patients with depression comorbid with diabetes or cardiovascular disease.
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Karina Lovell appraises the first UK RCT of computerised cognitive behavioural therapy (cCBT) for depression in children and young people, which shows a clinically meaningful improvement in depression and anxiety.
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Alex Langford reflects on the media hype surrounding a new RCT of the NAVIGATE intervention; a comprehensive, multidisciplinary, team-based treatment approach for first episode psychosis.
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