Ioana Cristea takes a closer look at a recent non-inferiority RCT, which compares mindfulness-based cognitive therapy (MBCT) plus discontinued antidepressants versus MBCT and maintenance antidepressants.
[read the full story...]Long-term psychoanalytic psychotherapy for treatment-resistant depression
Sarah McDonald presents the results of the Tavistock Adult Depression Study; a pragmatic RCT of long-term psychoanalytic psychotherapy for treatment-resistant depression.
[read the full story...]Nicotine patches, Varenicline and combination NRT: as good/bad as each other?
Paul Christiansen considers the findings of a recent RCT, which evaluates the effects of nicotine patches versus varenicline versus combination nicotine replacement therapy on smoking cessation at 26 weeks.
[read the full story...]School-based CBT for anxiety and low mood: the FRIENDS programme
Alan Underwood appraises a recent RCT of the effectiveness and cost-effectiveness of a school-based CBT programme (FRIENDS) to help prevent anxiety and low mood in children.
[read the full story...]Cognitive therapies for depression in adults: let’s just stick to the facts
Ioana Cristea reviews the NIHR-DC Highlight on cognitive therapies for depression, published online today, which summarises three NIHR-funded trials (REEACT, CoBalT and PREVENT) looking at cCBT, CBT and MBCT for depression in adults.
[read the full story...]Cognitive stimulation therapy for dementia
Clarissa Giebel summarises a multicentre RCT that assesses the clinical effectiveness and cost-effectiveness of individual cognitive stimulation therapy for dementia.
[read the full story...]Aripiprazole for treatment-resistant depression in older adults
Sarsha Wilson publishes her debut blog about a recent RCT on the efficacy, safety and tolerability of augmentation pharmacotherapy with aripiprazole for treatment-resistant depression in later life.
[read the full story...]A new MANTRA for treating anorexia nervosa? The MOSAIC study
Helen Bould considers the findings of the MOSAIC RCT that compares the Maudsley Model of Anorexia Nervosa Treatment for Adults (MANTRA) with Specialist Supportive Clinical Management (SSCM) in outpatients with broadly defined Anorexia Nervosa.
[read the full story...]Empowering patients can lead to fewer hospital readmissions, according to small RCT
Clarissa Giebel presents the findings of a small RCT that evaluates the impact of a social work care coordination intervention on hospital readmissions in older adults.
[read the full story...]Lamotrigine, quetiapine and folic acid for bipolar depression: the CEQUEL trial
Michael Ostacher considers the findings of the CEQUEL trial, which asks: Does lamotrigine treat bipolar depression when added to quetiapine, and does adding folic acid help any more?
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