Omega-3 supplements for the prevention of psychosis: another trial shows no benefit, so is it time to move on?

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David Mongan reports on a recent trial of omega-3 supplementation for the prevention of psychosis in people at ultra-high risk, which finds no evidence of a positive effect. He reflects on these findings and considers what’s next for the field.

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KarXT: an innovative and promising treatment for schizophrenia

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Nicola Rizzo Pesci and Andrea Cipriani summarise findings from the EMERGENT-2 trial spotlighting a promising new drug treatment for schizophrenia.

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ACT now for MND: acceptance and commitment therapy can improve quality of life for people with motor neuron disease

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Dona Matthews summarises a recent trial which suggests that Acceptance and Commitment Therapy can maintain or improve quality of life for people with early stage motor neuron disease.

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Can self help apps PROMOTE wellbeing or PREVENT illness in young adults?

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Kirsten Lawson summarises the ECoWeB PROMOTE and PREVENT trials in relation to self-helps apps for promoting wellbeing and preventing mental ill health among young adults.

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Apps for depression and anxiety: big new meta-analysis supports effectiveness

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In their debut blog, Lee Valentine summarises a large-scale updated meta-analysis investigating the effectiveness of mental health apps for depression and anxiety.

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Is my depression the same as your depression? Network analysis finds individual variation in how symptoms aggravate each other over time

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Giulia Piazza and Jonathan Roiser explore a recent network analysis and ecological momentary assessment study, which provides clear evidence that the relationships between depressive symptoms vary between individuals with depression who are matched on overall depression severity.

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Predicting antidepressant response using artificial intelligence

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Holly Fraser discusses new findings on whether and how we can predict antidepressant response using artificial intelligence.

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Digital self-help for bulimia recovery: encouraging results for waiting list management

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In her debut blog, Ana Julia Ferreira summarises a randomised controlled trial investigating the effectiveness of a digital self-help intervention for improving bulimic-spectrum disorder symptomatology while on a treatment waiting list.

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The great unknown? Assessing suicide risk in trials of psychological interventions for depression

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Derek de Beurs explores a meta-analysis which finds that randomised controlled trials of psychological interventions for depression rarely report assessments of suicide.

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Digitally augmented CBT for child anxiety is more efficient and no less effective than typical parent-led CBT

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Helen Dodd summarises a recent non-inferiority randomised controlled trial led by Cathy Creswell, which investigated the effectiveness of digitally augmented parent-led CBT for child anxiety.

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