Samei Huda mulls over a recent RCT on the effects of older and newer antipsychotics on quality of life in schizophrenia. The study finds a different result to the 10-year old CUTLASS trial; namely that second generation antipsychotics may be superior to first generation antipsychotics in terms of improving quality of life for people with schizophrenia.
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Alex Langford explores the emerging findings from a recent meta-analysis looking at the efficacy and safety of antidepressants added to antipsychotics for people with schizophrenia and schizophrenia-like psychosis.
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Murtada Alsaif summarises a recent 4-week long phase II randomised controlled trial of ITI-007 for the treatment of schizophrenia, which contains some positive results for this novel intervention.
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Emily Stapley presents the findings of a trial which looks at the effectiveness of an integrated telehealth service for patients with depression.
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Eight different assessment tools were used to assess quality of life for this review of the impact of periodontal disease on quality of life. 28 out of 37 studies reported a significant effect with 8 studies reporting an increasing impact with greater disease severity or extent.
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Jean Wong summarises a Cochrane systematic review, which suggests that exercise improves pain, function and quality of life in those with knee osteoarthritis.
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David Steele reports on a recent cross-sectional study, which found that stigma was linked with increased psychological distress and poorer quality of life in people with intellectual disabilities.
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Clarissa Giebel analyses a qualitative study of how functional alterations impact quality of life in Alzheimer disease.
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Jo Moriarty reviews two cohort studies comparing experiences of caregivers of young onset dementia with those of later onset dementia.
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Ian Hamilton reviews a recent long-term US study of integrated care for people with a dual diagnosis of substance use and schizophrenia, which concludes that recovery is possible, but it takes time.
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