Quetiapine may pip lithium to the post for augmentation in ‘treatment resistant depression’: results from the LQD study

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Kirsten Lawson and Douglas Badenoch review the new randomised controlled trial by Cleare et al, published today in The Lancet Psychiatry, directly comparing the clinical and cost effectiveness of lithium and quetiapine as augmentation treatments for patients with ‘treatment resistant depression’.

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Are apps for depression and anxiety worth the money?

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Andres Fonseca summarises a recent RCT which finds that apps for depression and anxiety in an IAPT service can be effective and cost effective.

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We can safely deliver therapy to suicidal inpatients, but we still don’t know if it works

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John Baker reviews a pilot randomised controlled trial of cognitive-behavioural suicide prevention therapy for mental health inpatients, which found that the therapy was acceptable and feasible to deliver.

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Collaborative care for depression: acceptable, effective and affordable

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Ben Hannigan writes his debut blog on the CADET cluster RCT, which investigates the clinical effectiveness and cost-effectiveness of collaborative care for depression in UK primary care.

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Are Internet interventions cost-effective for mental health?

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Chris Sampson looks at a systematic review of the economics of Internet interventions for common mental health problems such as depression and anxiety.

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Away from crime and into treatment: diversion and aftercare for drug-using offenders

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Can we steer drug-using offenders away from crime and into treatment? Chris Sampson explores a study of the cost-effectiveness of diversion and aftercare programmes for offenders using class A drugs.

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Do perinatal mental health problems cost the UK £8 billion per year?

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A recent report estimated the societal cost of perinatal mental health problems to be £8 billion, but should we believe it? Chris Sampson advises caution.

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CBT in primary care is cost-effective for treatment-resistant depression

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Elf economist Chris Sampson reports on the economic evaluation of the CoBalT RCT, which finds that CBT is cost-effective for treatment resistant depression in primary care.

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Health effects of depression: keeping economists’ models on track

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Health Economist Christopher Sampson reports on a recent systematic review and meta-analysis, which shows health-related quality of life utility values vary between studies and economic models should consider this.

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Cost-effectiveness of self-management for chronic pain in an aging population

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Chronic pain is a major health concern, which increases in prevalence and impact with age. This is important as chronic pain can result in a significant decrease in function and quality of life along with an increase in use of health and social care. Self-management is a potentially inexpensive form of pain management and it [read the full story…]