This review comparing the effectiveness of root canal treatment outcomes in teeth with a vital pulp versus a necrotic pulp included 28 studies. No differences between vital and necrotic pulps were seen for tooth survival. No studies reported on tooth function, adverse effects or oral health related quality of life (OHRQoL).
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This review investigating the incidence of and influential factors on pulp necrosis and periapical pathosis of vital teeth following indirect restorations included 37 studies. The findings suggest an overal incidence of pulpal necrosis of 5.02% (3.70 to 6.52%).
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This review comparing stepwise removal (SWR) and selective removal (SCR) of deep carious lesions in primary and permanent teeth included 9 RCTs. The findings suggest that SCR may be more succesful than SWR but they should be interpreted cautiously because of the limited number of studies for some outcomes.
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This review evaluating the evidence to support the possibility that orthodontic tooth movements could induce pulp necrosis included 12 studies. While the findings indicate there is evidence that these treatments do not induce pulp necrosis it has low to very low quality.
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This review of success and survival rates and complications of autotransplantation of teeth with incomplete root formation included 32 observational studies only 5 of which were considered to be of high quality. Good success rates were noted but findings should be interpreted cautiously
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This review of regenerative endodontic treatment (RET) or mineral trioxide aggregate (MTA) apical plug (MAP)in the treatment of teeth with pulp necrosis and open apices used broad inclusion criteria. 144 studies were identified suggesting promising outcomes. However the quality of the available evidence is very low and more high quality research is needed.
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