Ruby Tsang summarises a recent longitudinal study of trajectories of inflammation in youth and risk of mental and cardiometabolic disorders in adulthood, which finds that high levels of inflammation in childhood may be linked to an increased risk of psychosis, depression and insulin resistance in early adulthood.
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Magda Skowronska summarises a recent systematic review which finds that cumulative trauma could lead to earlier onset of bipolar disorder. A review that has important implications for mental health professionals.
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Lorna Staines discusses a recent Swedish cross-sectional study of 16,255 adolescent twins, which looks at the mental health risks of using psychedelics in the real world.
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Kalya Win Aung, Angela Kibia and Dorothy Williams consider a systematic review and network meta-analysis published by the Lancet Psychiatry on psychological and psychosocial interventions for treatment-resistant schizophrenia.
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Laura Naysmith summarises a study of menopausal hormone therapy (also known as HRT), which suggests the treatment is linked with reduce the risk of psychosis relapse in menopausal women.
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David Mongan reports on a recent trial of omega-3 supplementation for the prevention of psychosis in people at ultra-high risk, which finds no evidence of a positive effect. He reflects on these findings and considers what’s next for the field.
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Nuala Murray explores a recent Australian case-control study that looks at the associations between changes in gut microbiota and schizophrenia diagnosis, treatment resistance, and clozapine response.
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Amy Ferguson summarises a recent study published by researchers in Birmingham, which suggests that persistent shorter sleep in childhood may increase the risk of psychotic experiences.
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Nicola Rizzo Pesci and Andrea Cipriani summarise findings from the EMERGENT-2 trial spotlighting a promising new drug treatment for schizophrenia.
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Ana Veic looks at an updated systematic review which suggests that patients with psychosis display cognitive difficulties very early in the disease process, and concludes this variation in cognitive function should prompt individual clinical assessments to optimise care.
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