This review and network meta-analyses of the effectiveness of self-applied dentifrices in the management of dentine hypersensitivity included 68 studies. Findings indicated that formulations including stannous, potassium +/- stannous, and arginine result in significant short ( 2-weeks) and long term inprovements. However the studies were hetrogeneous and only 4 were at low risk of bias.
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This network meta-analysis comparing the effect of different desensitising toothpastes on dentine hypersensitivity included 30 RCTs. The findings suggest that toothpastes containing nano-hydroxyapatite or arginine may be the most effective. However additional larger studies are required.
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This review evaluating the effectiveness of desensitising toothpastes included 53 RCTs. Most agents with the exception of those containing strontium or amorphous calcium phosphate were effective in relieving dentine hypersensitivity compared with negative controls.
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Dementia is a huge issue. As our population ages, the incidence of the disease is on the increase and attempts to prevent and treat the condition with drugs have not been as successful as we hoped. A lot of effort has gone into investigating ways in which lifestyle factors such as diet can impact on [read the full story…]
