This review aimed to assess the effect of bioactive glass on bone and periodontal regeneration and included 20 RCTs. The included studies were small, involved numerous comparisions with only two being at low risk of bias. The findings showed a statistically signiciant benefit for probing depth with bioglass but this may not be clinically significant and the limited quality of thei included studies mean the findings should be interpreted cautiously.
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This review of canine retraction after maxillary first premolar extraction in adolescent and adult orthodontic patients using fixed appliances included 50 RCTs. However only a small number of studies contributed to the estimate of 4.98 months (95%CI; 2.92 to 12.88 months) to complete canine retraction.
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This Cochrane review update looked at local interventions used for the prevention and treatment of alveolar osteitis (dry socket) following tooth extraction. 49 RCTs were included providing moderate certainty evidence for chlorhexidine rinses and gel for probably reduction in dry sockets.
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This Cochrane review update of interventions for the prevention or treatment of medication-relatesd osteonecrosis of the jaw (MRONJ) included 13 RCTs. However the studies provided insufficient to either claim or refute a benefit of the interventions tested for prophylaxis or treatment of MRONJ.
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This review of platelet-rich fibrin (PRF) to reducedpostoperative complications following lower third molar surgery included 6 RCTs.
The findings are consistent to other reviews finding that PRF derivative may lead to improvements in postoperative outcomes from third molar surgery but the amount of evidence is limited.
This review of the effectiveness of leukocyte-and platelet-rich fibrin (L-PRF) and advanced-platelet-rich fibrin (A-PRF) in mandibular third molar extraction included 10 RCTs. While the findings suggest some benefits the studies are small and limited in number so the findings should be interpreted cautiously.
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This review of different pulpotomy dressing agents for pulpotomy treatment in immature permanent teeth. While the review suggested that the various agents tested had similar success rates the findings should be viewed cautiously as all the studies were at high risk of bias.
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This review of the effectiveness of platelet-rich fibrin (PRF) in reducing postoperative complications of third molar surgery included 10 small RCTs suggesting that PRF may reduce but not prevent some complications.
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This blog on a review of the efficacy of platelet rich fibrin (PRF) in oral surgery procedures was prepared by MSc Students from @UClanDentistry during a workshop with the @TheDentalElf. The review includes 30 small studies of limited quality more high quality studies are needed to assess effectiveness.
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38 RCTs were included in this Cochrane review of the effects of autologous platelet concentrates (APC) used as an adjunct to periodontal surgery. Very low quality evidence was found for two approaches involving open flap debridement.
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