How do antiresorptive drugs affect the success of dental implants?

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Antiresorptive drugs, used to treat osteoporosis and metastatic bone disease, can complicate dental implant procedures by increasing the risk of medication-related osteonecrosis of the jaw (MRONJ). This systematic review investigates how these drugs affect the success and complications associated with osseointegrated dental implants. Key findings Antiresorptive drugs significantly increase the risk of (MRONJ), accounting for [read the full story…]

Dental implants: survival rates in patients with osteoporosis

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15 observational studies were included in this review of implant survival in patients with osteoporosis. while the findings suggest no difference compared to healthy patients the quality of the included studies is low so the findings should be interpreted cautiously.

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What impact are psychotropic drugs having on our physical health?

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John Baker summarises the findings of a recent review of people with schizophrenia, bipolar disorder and depression. The study looks at the adverse effects on physical health of psychotropic drugs (antipsychotics, antidepressants and mood stabilisers).

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Higher risk of vitamin D deficiency for people with learning disabilities

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To date there has been little research on vitamin D deficiency in people with learning disabilities. In this debut blog by Brant Cebulla, we look at a new case control study which sets out to answer some key questions and consider areas for further research.

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Schizophrenia and osteoporosis: sticks and stones may break my bones…

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Chris Pell summarises a recent meta-analysis of prevalence estimates and moderators of low bone mass in people with schizophrenia. The study finds a significantly increased risk of osteoporosis in people with schizophrenia.

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Critical summaries from the American Dental Association-Center for Evidence-based Dentistry-Jan 2013

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A number of new critical summaries have been made available on the ADE-EBD website of the past few weeks. The first is an appraisal of a 2010 review by Martínez-Maestre et al. that looked at the association between dental bone loss and systemic osteoporosis.  The reviewer highlighted that this was a weak review of observational [read the full story…]

Models of care for the secondary prevention of osteoporotic fractures

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Saturday 20 October is World Osteoporosis day raising awareness about osteoporosis and fragile bones. In a previous blog The Musculoskeletal Elf discussed Best risk assessment advice for people with fragility fractures. However, despite the availability of effective treatments it appears that the majority of people presenting with a minimal trauma fracture (also known as ‘osteoporotic’, [read the full story…]

Best risk assessment advice for people at risk of fragility fractures

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This week sees the inaugural global congress in Berlin of the Fragility Fractures Network – a Global Network to Improve Fragility Fracture Management and Prevention. Osteoporosis is a condition resulting in an increased risk of skeletal fractures due to a reduction in the density of bone tissue.  The risk of osteoporosis starts to increase in [read the full story…]