This review of the effects of micro-osteoperforation on the rate of tooth movement in patients undergoing orthodontic treatment included 6 RCTs. Although meta-analysis found a small statistical benefit in favour of micro-osteoperforation in the short term the clinical benefits particularly over the duration of a course of treatment remain unclear.
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This review of direct and indirect bonding techniques for orthodontic backet placement included 8 small RCTs of limited quality suggesting no significant difference in bracket placement accuracy, oral hygiene status and bond failure rate.
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This review of the efficacy of preventive interventions against the development of white spot lesions (WSLs) during fixed appliance orthodontic treatment included 23 RCTs tha majority of which were at high risk of bias. The findings suggest some benefit from sealants and fluoride varnishes but more high quality research is neeeded.
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This review of bone-borne/hybrid tooth-bone-borne rapid maxillary expansion (RME) with conventional tooth-borne RME in the treatment of maxillary deficiency included 6 small RCTs suggesting some advantage for bone-borne/hybrid tooth-bone-borne appliances.
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This review of mini-screws for orthodontic anchorage included 7 small RCTs of variable quality with the findings suggesting that mini-screws are more effective than conventional approaches
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This review of the efficiency of the vibrating devices in accelerating orthodontic tooth movement identified 6 RCTs the majority being short term and at high risk of bias. The RCTs suggested no difference with the use of vibrational devices.
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This review of different methods for reducing pain and discomfort during removal of fixed orthodontic appliances included 6 RCTs providing weak evidence for pre-debonding analgesia and other approaches.
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This review of professional topical fluoride application to prevent/reverse enamel white spot lesions during orthdontic treatment included 11 RCTs suggesting a reduction of in incidence of between 25–30% .
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Two surgical approaches ( open and closed) for palatally displaced canines were compared in this multi-centre RCT. No differences in operating time was seen between the two approaches but those in the open group had more pain.
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8 mainly observational studies were included in this review of he effectiveness of clear aligners compared with fixed appliances for orthodontic treatment. The findings suggest no difference between to two approaches however the quality of the availabel evidence is low to very low.
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