This review of the efficacy of curcumin in improving symptoms in patients with oral submucous fibrosis (OSF) included 13 RCTs. The main findings suggest no significant difference between curcumin and controls although the studies are small and heterogenous.
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This review looked at the efficacy of photodynamic therapy (PDT) for the treatment or oral lichen lplanus (OLP) and compares PDT with steroid therapy. 16 studies were included with the findings suggesting that photodynamic therapy may offer patients with OLP improved pain relief and better efficacy compared to topical corticosteroids.
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This review of treatments for actinic cheilitis included 29 mainly observational studies providing little evidence to identify the best treatment approaches.
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This review evaluating the evidence on the effectiveness of curcumin in the management of oral submucous fibrosis included 6 small RCTs providing inconclusive evidence of a potential benefit.
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This review of the malignant transformation rate of oral leukoplakia included 24 studies, the majority of which were retrospective. The range of malignant transformation was between 0.13% and 34.0%. The quality of the available data was limited and there is a need for higher quality well-reported studies.
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This review of photodynamic therapy (PDT) for oral premalignant lesions only identified a small number of poor quality studies that provide insufficient evidence for the effectiveness of PDT for the management of oral premalignant lesions.
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