Small trial suggests limited short-term benefit from 0.1% pilocarpine mouthwash for xerostomia

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Xerostomia is a subjective sensation of dry mouth, this is a common symptom particularly in older adults and has a variety of causes. Pilocarpine is a cholinergic agonist that non-selectively binds to muscarinic receptors in smooth muscles in the gastrointestinal, urinary and pulmonary systems and stimulates the production of secretions from the salivary and sweat [read the full story…]

New Cochrane Protocol April 2013

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Just one new protocol in the April issue of the Cochrane Library from the Oral Health Group.  The aim of this review will be to assess the effects of interventions for the management of patients with taste disturbances. The review is planning to look at pharmacological and non-pharmacological interventions.   The primary outcomes being looked at [read the full story…]