Oral lichen planus: How common is it worldwide?

Lichen Planus -histopathology

This review of the global prevalence of oral lichen planus (OLP) included 66 observational studies providing an estimate of prevalence of 1.01% (0.74 to 1.32%).

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Botulinum toxin for management of temporomandibular disorders

shutterstock_128569418

This review of botulinum toxin (BTX) in the management of temporomandibular joint disorders (TMD) included 7 small RCTs of low quality. high quality well reported RCTs with larger sample sizes and longer follow times are needed to properly assess the effectiveness of BTX in the management of TMD.

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Antifungal drugs for oral candidiasis

Candida Albicans

This network meta-analysis of the efficacy of antifungal drugs on oral candidiasis included 31 RCTs of overal low quality suggesting that fluconazole may be the most effective.

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Oral leukoplakia: Malignant transformation rate

OLYMPUS DIGITAL CAMERA

This review of the rate of malignant transformation of oral leukoplakia included 34 many retrospective observational studies. The estimated mean malignant transformation rate was 9.7% (95%CI; 7.8% to 11.7%).

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Oral candidiasis: Are probiotics effective?

Candida albicans

This review of the the efficacy of probiotics on oral Candida spp. includes 12 RCTs and suggests a possible benefit. However the quality of the evidence is limited so the findings should be intepreted cautiously.

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Oral lichen planus: malignant transformation rate

Lichen_planusWickham's

This review of the malignant transformation rate of oral lichen planus and associated risk factors included 33 studies. Using a strict definition the authors found a malignant transformation rate of 0.44%.

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Oral Lichen Planus: Is treatment with corticosteroids safe and effective?

Lichen_planusWickham's

This Cochrane review of the efficacy and safety of corticosteroids for the treatment of people with oral lichen planus(OLP) included 35 RCTs suggesting that they may be more effective than placebo for reducing the pain of symptomatic OLP but the reliability of the finding is low.

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Guideline: Antibiotics for Dental Pain and Swelling

shutterstock_64158991 question mark pills tablets

This new guideline from the American Dental Association is about the the appropriate use of systemic antibiotics for the urgent management of symptomatic irreversible pulpitis with or without symptomatic apical pulpitis, pulp necrosis and symptomatic apical periodontitis and pulp necrosis and localized acute apical abscess.

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Vitamin D deficiency: Is it a risk factor for recurrent aphthous stomatitis?

Researchers in this study wanted to see if people with learning disabilities had higher levels of vitamin D deficiency than the general population

This review of a possible association between vitamin D deficiency and recurrent aphthous stomatitis (RAS) included 5 case control studies providing limited evidence that low levels of serum vitamin D might be a risk factor for RAS.

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COX-2 inhibitors for pain management after third molar removal

Many drugs are licensed for use in Generalised Anxiety Disorder (GAD), but it is unclear what works best.

This review comparing the efficacy of Cox-2 inhibitors with ibuprofen after third molar removal included 12 RCTs suggesting that COX-2 inhibotors and Ibuprofen provide similar pain relief at 6, 8, and 12 h after third molar removal.

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