Only weak evidence of the effectiveness of any treatments for erosive lichen planus

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Lichen planus (LP) is an inflammatory condition that affects the skin and the squamous epithelium of mucosal surfaces lining the mouth, ears, eyes, and nose as well as the gastrointestinal and anogenital tracts. Two main patterns of inflammation are described:  the plaque (raised) type and the erosive (raw) type, although bullous, blistering, or hypertrophic (thickened)types [read the full story…]

4% articaine and 2% lidocaine with epinephrine have similar effectiveness in achieving anaesthesia in maxillary teeth

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The aim of the study was to compare the anaesthetic efficacy of buccal infiltrations of 4% articaine with epinephrine (1:100,000) and 2% lidocaine with epinephrine (1:80,000) in achieving anaesthesia in maxillary permanent teeth with irreversible pulpitis. Patients aged 16 years and over who presenting with irreversible pulpitis in one tooth and an asymptomatic vital tooth [read the full story…]

Stress associated with onset of recurrent mouth ulcers

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Recurrent aphthous stomatitis (RAS) is a common and painful oral disease. It is characterised by recurring mucosal ulceration in an otherwise healthy individual.  Its prevalence is commonly estimated to be between 5% and 25%  with a peak age of onset between 10 and 19 years although they may continue throughout the patient’s life span.  An [read the full story…]

Weak evidence for honey in prevention of oral mucositis for cancer patients radiotherapy

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Oral mucositis is a common side effect of  the treatment of malignancy with chemotherapy or radiotherapy. Two Cochrane reviews (see below) have looked more broadly at interventions for  prevention and treatment of this unpleasant side effect of treatment.  The aim of this review was to assess the protective effect of honey in head and neck [read the full story…]

Some evidence for the presence of hepatitis viruses A, B and C in oral fluids

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Viral hepatitis is caused by five distinct viruses (A-F) and they represent a significant worldwide healthcare problem. Three of the viruses hepatitis A, B and C (HAV, HBV, HCV) are the most common causes. Recently, there has been renewed interest in whether oral fluids can be considered as a source of viral hepatitis transmission.  There [read the full story…]

Little evidence for drug treatments for oral submucous fibrosis

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Oral Submucous fibrosis (OSMF) is a chronic disease caused by the use of areca nut. It  is associated with significant morbidity (including pain and reduced oral opening) and an increased risk for malignancy. The aim of this review identify the published literature on the role of various drugs in the treatment of oral submucous fibrosis. [read the full story…]

Some weak evidence for non-invasive psychosocial interventions in the management of chronic orofacial pain

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This Cochrane review  aimed to determine efficacy of psychosocial interventions in the management of chronic orofacial pain.   The authors highlight four recognisable symptom complexes of chronic orofacial pain that may coexist: temporomandibular disorder (myofacial face pain); atypical facial pain (atypical facial neuralgia); atypical odontalgia (phantom tooth pain); and burning mouth (oral dysaesthesia, glossodynia, glossopyrosis). Searches [read the full story…]

Improvements in dry mouth seen with night guard and/or BET containing mouthwash

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Xerostomia is a common condition that affects many adults. It is frequently caused by autoimmune diseases such as Sjögren’s syndrome and rheumatoid arthritis or as a result of drug-related side effects. The aim of the present study was to evaluate the efficacy and safety of an intraoral device and a Betaine (BET) containing mouthwash in [read the full story…]

Using ice chips reduces oral mucositis in patients undergoing chemotherapy

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Cancer treatment is increasingly effective but is associated with short and long term side effects. Oral side effects remain a major source of illness despite the use of a variety of agents to prevent them. One of these side effects is oral mucositis (mouth ulcers). The aim of this study was to assess the effect [read the full story…]

Very low quality evidence for the efficacy of most neurosurgical procedures for trigeminal neuralgia

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The trigeminal nerve is the fifth cranial nerve and one of the largest in the head. It provides sensation to the face and  is called trigeminal because it splits into three main branches. When neuralgia (nerve pain) occurs in the trigeminal nerve it causes severe and sudden face pain. It has an incidence rate of [read the full story…]