This umbrella review of the proportion of oral cancer development in oral submucous fibrosis patients included 4 systematic reviews published between 2019 and 2022. Mean values for malignant transformation across the reviews range from 4.2% to 6%.
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This review of the prevalence of oral leukoplakia reported from 1996 to 2022,by continent, definition, age, and living habits included 69 studies. The findings provided a global pooled estimate for prevalence of 3.41% (95%CI: 2.65 to 4.26%).
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This review of the rate of malignant transformation (MT) of oral leukoplakia and potential risk factors included 26 mainly retrospective studies. The findings indicate a MT of 7.2% (95%CI; 5.40 to 9.10%) similar to those of another recent review whihc estimated MT as 9.8% (95%CI; 7.9 to 11.7%).
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In this blog Rebecca Manson takes a look at a review assessing the global prevalence of geographic tongue. 14 studies were included suggesting a prevalence of 3% (95%CI 0.4% to 5.5%)
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In this blog we look at a review of the malignant transformation rate (MTR) for oral submucous fibrosis (OSF). The review included 16 studies estimating the malignant transformation rate as 6% (95%CI: 2% to 10%)
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This review of the malignant development rate of oral erythroplakia and associated risk factors included 10 studies involving a total of 441 patients. Meta-analysis of 3 studies suggest a malignant development rate = 19.9% (95%CI; -1.6% to 41.4%).
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This review assessing the effectiveness of topical interventions in the management of burning mouth syndrome (BMS), based on the core outcome domains recommended by the Initiative on Methods, Measurement, and Pain Assessment in Clinical Trials (IMMPACT) includes 8 RCTs and higlights the need to apply standardised outcome measures in future studies.
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In this blog Iris Vaid looks at a review of chronic ulcerative stomatitis (CUS) a rare mucous membrane condition that presents clinically as non-specific ulcerated or erosive lesions. The review included 81 cases reported in 25 papers.
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This review comparing the efficacy and safety of topical antifungal drugs for oral candidiasis in children and adults included 11 RCTs 9 of which concerned adults and 2 children. The findings support the use of fluconazole and amphotericin B for adults.
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Iris Vaid takes a look at this review of whether e-cigarettes have a negative impact on the cells in the head, neck, and mouth. 16 in-vitro studies showed that oral cells exposed to e-cigarettes showed aberrant cell morphology, reduced cell viability, and increased apoptosis and/or necrosis.
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