David Mongan reports on a recent trial of omega-3 supplementation for the prevention of psychosis in people at ultra-high risk, which finds no evidence of a positive effect. He reflects on these findings and considers what’s next for the field.
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Céline Wessa reports on a recent systematic review of pharmacological anti-inflammatory treatment in children and adolescents with depressive symptoms, which has some promising results.
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Gerard Clarke explores a recent study which looks into the interplay of metabolome and gut microbiome in individuals with major depressive disorder.
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Daisy Crick summarises a recent paper on the casual relationship between polyunsaturated fatty acids and depression.
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This review assessing the adjunctive effect of omega-3 (ω-3) fatty acids and non-surgical periodontal therapy (SRP)on probing pocket depth (PPD) and the clinical attachment level (CAL) included 10 RCTs. The findings suggest that adjunctive ω-3 fatty acids provides a 0.39 mm improvement in PPD and 0.41 mm of CAL gain.
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In his debut blog, Richard Meiser-Stedman explores a recent Cochrane systematic review which finds no evidence for the use of medication to prevent the onset of PTSD in people who have been exposed to a traumatic event.
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This review assessing the impact of dietary omega-3 fatty acids as an adjunct to non-surgical periodontal treatment when compared with periodontal treatment alone included 10 trials ivolving a total of 467 patients. The studies found statistically significant improvements in clinical attachment level (CAL) and periodontal probing depth (PPD) but the studies are generally small and short-term.
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Ashlee Negrone summarises a systematic review and meta-analysis on omega-3 supplements for depression and anxiety in adults, and briefly introduces their Active Ingredients project on omega-3 for youth depression and anxiety.
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Carla McEnery summarises a systematic review and meta-analysis of interventions and social functioning in youth at risk of psychosis.
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Joff Jones summarises a recent systematic review, which looks at the evidence for a wide range of non-pharmacological treatments for ADHD. The review finds the strongest evidence for diet, child/parent training and behavioural interventions.
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