Nicotine replacement therapy – oral side effects

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For inpatients with psychiatric symptoms of moderate severity, the study suggests those using nicotine inhalers were most successful overall in their quit attempts. There were no severe adverse reactions to the NRTs.

This review of the evidence on possible association between locally delivered nicotine replacement therapy(NRT) and oral side effects included 28 RCTs. Most of the RCTs were at high risk of bias mainly because of allocation concealment concerns. Reported oral side effects including oral soreness, gastric reflux or vomiting, and mouth or throat irritation.

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Nicotine patches, Varenicline and combination NRT: as good/bad as each other?

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Paul Christiansen
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Paul Christiansen considers the findings of a recent RCT, which evaluates the effects of nicotine patches versus varenicline versus combination nicotine replacement therapy on smoking cessation at 26 weeks.

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