Personalised medicine: a transformative era in dementia research

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Nagina Khan writes her debut elf blog on a recent study in the British Journal of Psychiatry about the individual course of neuropsychiatric symptoms in people with Alzheimer’s and Lewy body dementia.

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Alternatives to medication for agitation in dementia

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Andrés Fonseca summarises the findings of a recent systematic review of the clinical effectiveness and cost-effectiveness of sensory, psychological and behavioural interventions for managing agitation in dementia.

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What should we prescribe for neuropsychiatric symptoms in Alzheimer’s disease?

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Psychiatrist Andrés Fonseca considers how his clinical practice should change, after reading a systematic review and meta-analysis of drug treatment for neuropsychiatric symptoms in Alzheimer’s disease

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Which (if any) drugs should we use for agitated or aggressive behaviour in dementia?

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This is a dilemma I frequently face when I am called out to see someone with dementia on the ward or living in a nursing home. On the one hand I am thinking that anything I use can potentially have serious side-effects and will probably lead to increased health risks and increased mortality. On the [read the full story…]

Non-drug treatments delivered by family carers can improve neuropsychiatric symptoms in people with dementia

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About three-quarters of people with dementia are affected by neuropsychiatric symptoms (NPS). This is a broad group of symptoms including depression, sleep problems, apathy, psychosis and aggression. Of course, many people with dementia still live at home and are cared for by their spouse or other primary carer. These neuropsychiatric symptoms can have a major impact [read the full story…]