A new model for schizophrenia?

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Schizophrenia is a complex disorder (or, more likely, group of disorders) that has reality distortion at its core. Efforts to establish the cause of schizophrenia have been ongoing for more than a century, and many models have come and gone in that time (not for nothing has schizophrenia been called ‘the graveyard of neuropathologists’ (Plum, [read the full story…]

Vitamin D deficiency in psychosis: our current (limited) understanding according to the latest meta-analysis.

Get ready to amend your dopamine hypothesis and stop trying to wrap your neurons around the role of glutamate in the brain.  The rising star of the neurobiological schizophrenia literature is…. Vitamin D.  Yes, really. The more sceptical amongst you (including me) may feel that finding a vitamin deficiency in psychosis patients is perhaps not [read the full story…]