This review of the the effect of herbal mouthwashes as an adjuvant to oral hygiene measures in reducing plaque and gingival inflammation in adults included 20 RCTs suggesting that most agents performed better than placebo.
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44 RCTs were included in this Cochrane review assessing interventions for the prevention and control of halitosis. Only low to very-low cetrainty evidence was identified so conclusions regarding the superiority of any intervention could not be drawn.
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This review of self-applied topical fluorides for the prevention reversal of enamel white spot lesions during fixed orthodontic treatment included 3 RCTs two of which were at high risk of bias.
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This review of the effectiveness of chlorhexidine mouthwash with an anti-discoloration system (ADS) is effective in preventing extrinsic tooth surface discoloration included 13 RCTs with the findings suggesting that ADS reduces staining but did not affect its properties with respect to gingival inflammation and plaque scores.
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This review of the efficacy of different anti-plaque chemical agents in managing gingivitis included 32 RCTS of toothpastes and 19 of mouthrinses suggested greater benefits with some agents.
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This review comparing the effectiveness of Salvadora persica-containing mouthrinses against chlorhexidine or placebo included 19 studies providing low to very low quality evidence of its effectiveness.
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This review of the efficacy of aloe vera mouthrinse on plaque and gingival inflammation includes 6 RCTS providing very low quality evidence that aloe vera mouthwash is comparable to chlorhexidine in reducing gingival inflammation.
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This review of the efficacy of a chlorhexidine mouthwash containing sodium fluoride compared to a chlorhexidine mouthwash alone includes 10 small short term studies that suggests the findings are similar for both preparations.
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51 studies were included in this Cochrane review of chlorhexidine mouthwash as an adjunct to mechanical oral hygiene measures. The review provides high quality evidence for a large reduction in the build-up of plaque at 4 to 6 weeks or 6 months. There is also high quality evidence of a moderate reduction in gingivitis in patients with mild gingivitis which may not be clinically important.
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This review of chlorhexidine (CHX) for prevention & treatment of oral mucositis included 12 RCTs with 9 contribution to the meta-analysis. CHX was not significantly effective in preventing mucositis or reducing its severity.
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