This review of self-applied topical fluorides for the prevention reversal of enamel white spot lesions during fixed orthodontic treatment included 3 RCTs two of which were at high risk of bias.
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This review of the efficacy of different anti-plaque chemical agents in managing gingivitis included 32 RCTS of toothpastes and 19 of mouthrinses suggested greater benefits with some agents.
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This review comparing the effectiveness of Salvadora persica-containing mouthrinses against chlorhexidine or placebo included 19 studies providing low to very low quality evidence of its effectiveness.
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This evidence-based clinical practice guideline on the non-restorative treatments for carious lesions in primary and permanent teeth from the American Dental Association provides 11 recommendations.
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This review of the efficacy of a chlorhexidine mouthwash containing sodium fluoride compared to a chlorhexidine mouthwash alone includes 10 small short term studies that suggests the findings are similar for both preparations.
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51 studies were included in this Cochrane review of chlorhexidine mouthwash as an adjunct to mechanical oral hygiene measures. The review provides high quality evidence for a large reduction in the build-up of plaque at 4 to 6 weeks or 6 months. There is also high quality evidence of a moderate reduction in gingivitis in patients with mild gingivitis which may not be clinically important.
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This review of the effectiveness of chlorhexidine for prevention of dry socket after third molar removal includes 18 RCTs. The finding suggest a 47% (95%CI,38-55) reduction in cases following its use.
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38 RCTs were included in this Cochrane review update of oral health care in ventilated patients. High quality evidence was found to show that chlorhexidine mouthwash or gel reduces the risk of developing ventilator-associated pneumonia in critically ill patients from 25% to about 19%.
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63 RCTs contributed to this network meta-analysis of the effectiveness of anti-plaque agents. Results suggested that toothpastes containing triclosan-copolymer or chlorhexidine and mouthrinses containing essential oils or chlorhexidine had the most effect on plaque indicies at 6 months.
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This Cochrane review includes 37 RCTs and found regular supervised use of fluoride mouthrinse by children and adolescents is associated with a large reduction in caries increment in permanent teeth.
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