Commonly prescribed psychiatric drugs: do they work?

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John Baker summarises a review of commonly prescribed medication that covers seven psychiatric drugs, including antidepressants, antipsychotics, benzodiazepines, amphetamines, methylphenidate and cholinesterase inhibitors.

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What impact are psychotropic drugs having on our physical health?

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John Baker summarises the findings of a recent review of people with schizophrenia, bipolar disorder and depression. The study looks at the adverse effects on physical health of psychotropic drugs (antipsychotics, antidepressants and mood stabilisers).

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Medication for self-harm: new Cochrane review finds very limited evidence to support its use

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Dochka Hristova reports on a new Cochrane review of pharmacological interventions for self-harm in adults, which looks at the treatment effect on repetition of self-harm of antidepressants, antipsychotics, mood stabilisers and dietary supplements.

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Mood Matters: mood instability is common and associated with poor outcomes

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Farhana Mann summarises an observational study of mood instability in people with mental illness, which explores its relationship with days spent in hospital, frequency of admissions, the likelihood of being sectioned and the chance of being prescribed antipsychotics and mood stabilisers.

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Treatments for delusional disorder

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Andrew Shepherd summarises a Cochrane systematic review of treatments for delusional disorder, which finds only 1 small RCT looking at treating the condition with medication or psychotherapy compared to placebo.

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Pharmacotherapies for reducing cannabis dependence

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Kathryn Walsh reports on a recent Cochrane systematic review of pharmacotherapies for cannabis dependence, which concludes that there is a lack of evidence for all medications reviewed.

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Childhood adversity linked to psychotropic drug use in later life

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Andrew Jones summarises a large Finnish population-based cohort study, which finds that childhood adversities strongly predict the use of psychotropic drugs (such as antidepressants and antipsychotics) in adulthood.

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Medication for the maintenance treatment of bipolar disorder

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Elena Marcus summarises a recent network meta-analysis published in The Lancet of the comparative efficacy and tolerability of medication for the maintenance treatment of bipolar disorder.

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Antipsychotics and mood stabilisers may reduce violent crime

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John Baker reports on the first population based report of the positive effects of antipsychotic medication and mood stabilisers on reducing the risk of a conviction for violent crime, published in the Lancet in May.

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Treatment of bipolar in specialised outpatient mood disorder clinics substantially reduces readmissions to psychiatric hospitals

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There is a limited amount of good quality research being published about bipolar disorder, particularly investigating the early stages. Bipolar is associated with a high risk of relapse and this risk of relapse increases with the number of previous episodes. Observational studies suggest that early intervention may improve both course and outcome, but currently progression [read the full story…]