Suicide and mental illness in low- and middle-income countries

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Tessa Roberts summarises a recent a systematic review and meta-analysis, which looks into the prevalence of mental illness and suicidal behaviour in low- and middle-income countries.

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Are antidepressants safe? A new umbrella review of observational studies suggests they are, but we need more accurate data

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Andrea Cipriani and Anneka Tomlinson scrutinise a brand new umbrella review of the associations between antidepressants and adverse health outcomes, which suggests that antidepressants are safe for most people who experience mental health difficulties.

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In adults with major depression, antidepressants may increase the risk of suicide

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Douglas Badenoch explores a meta-analysis of follow-up data from clinical trials of antidepressants, which found a small but significant increase in suicide risk.

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Young people with autism suffer poorer sleep quality than their peers

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A group of UCL Masters students summarise a systematic review and meta-analysis of subjective and objective studies, which explores sleep problems in young people with autism spectrum disorders.

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Adolescent cannabis use and risk of depression and suicide

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Benjamin Janaway blogs about a major data analysis that links adolescent cannabis use with increased risk of depression and suicide. He considers the opportunities for early recognition of cannabis use and public intervention.

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Higher doses of antidepressants “not optimal”, according to new review

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Jonathon Tomlinson considers his options as a GP supporting people with depression and complex needs, after reading a new systematic review and dose-response meta-analysis, which suggests that higher doses of antidepressants bring maximum side effects with only marginal gains.

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New genes implicated in Alzheimer’s disease #LetsTalkMentalHealthII

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Byron Creese writes a #LetsTalkMentalHealthII blog about a recent genome-wide meta-analysis which identifies new loci and functional pathways influencing Alzheimer’s disease risk.

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Compulsory detention under the Mental Health Act: significantly more likely if you come from a BAME or migrant group

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Ian Cummins explores a recent international systematic review and meta-analysis, which highlights ethnic variations in compulsory detention under the Mental Health Act.

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Suicide risk assessment among psychiatric inpatients: pessimism around predictive power

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Alex Langford appraises a systematic review that looks at high-risk categories for suicide risk assessment among psychiatric inpatients.

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Rates of psychotic disorders: huge variability and important risk factors

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Emma O’Neill summarises a systematic review and meta-analysis of the incidence of psychotic disorders, which looks at the distribution of rates and the influence of gender, urbanicity, immigration and socio-economic level.

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