This umbrella review of the proportion of oral cancer development in oral submucous fibrosis patients included 4 systematic reviews published between 2019 and 2022. Mean values for malignant transformation across the reviews range from 4.2% to 6%.
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This review of the rate of malignant transformation (MT) of oral leukoplakia and potential risk factors included 26 mainly retrospective studies. The findings indicate a MT of 7.2% (95%CI; 5.40 to 9.10%) similar to those of another recent review whihc estimated MT as 9.8% (95%CI; 7.9 to 11.7%).
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In this blog we look at a review of the malignant transformation rate (MTR) for oral submucous fibrosis (OSF). The review included 16 studies estimating the malignant transformation rate as 6% (95%CI: 2% to 10%)
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This review of the malignant development rate of oral erythroplakia and associated risk factors included 10 studies involving a total of 441 patients. Meta-analysis of 3 studies suggest a malignant development rate = 19.9% (95%CI; -1.6% to 41.4%).
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Amoxicillin and metronidazole as an adjunct to full-mouth scaling and root planing, malignant transformation on oral lichen planus and toothbrushing to prevent ventilator-associated pneumonia was out most popular blogs between October to December 2021.
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This review of high quality studies of oral lichen planus malignant transformation rate included 10 observational studies. The findings found a higher level of malignant transformation in higher quality studies 2.28% (95%CI; 1.49 to 3.20) compared with reviews including lower quality studies 1.14% (0.84 to 1.49).
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This review of the evidence on the malignant transformation of oral proliferative verrucous leukoplakia included 17 mainly retrospective observational studies. The overall estimate for malignant transformation was 43.87% (95% CI; 31.93 to 56.13) but only 4 studies were at low risk of bias.
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This update of an earlier review of the malignant transformation rate of oral leukoplakia included 24 retrospective studies. The pooled proportion of malignant transformation was 9.8% (95%CI; 7.9 to 11.7%)
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Marianne Dobson in her first blog for the Dental Elf takes a look at a systematic review looking at the main clinical features of proliferative verrucous leukoplakia
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This review of the rate of malignant transformation of oral leukoplakia included 34 many retrospective observational studies. The estimated mean malignant transformation rate was 9.7% (95%CI; 7.8% to 11.7%).
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