Long term maintenance treatment with antipsychotics: a cautionary note from recent research

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The support of individuals with experience of psychosis is complex and relies on a combination of psychopharmacology (antipsychotic drugs), psychological therapies and social interventions. Antipsychotics will often be the first line treatment offered, with the intention of reducing psychotic symptom burden. Following the resolution of immediate symptoms the role of antipsychotics becomes less clear; should [read the full story…]

Cochrane review finds limited evidence to support valproate as a maintenance treatment for bipolar disorder

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Bipolar disorder is an affective disorder marked by cycles between mania and depression. It has an early onset, with mean age ranging from 19 to 29 (Offord, 2012) and a prevalence of 0.5% – 4.3% in primary care alone, stretching to 9.3% in some settings (Cerimele, Chwastiak, Dodson, & Katon, 2013). With its problematic recurring [read the full story…]

If I pay you, will you have your injection?

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Getting patients to take their medication as prescribed is notoriously difficult. Regardless of condition only about 50% of patients adhere to prescribed regimes. This is particularly the case in chronic or complex conditions worldwide and improving this problem has the potential to save considerable health burden and costs. Adherence in mental health is no different. [read the full story…]

New guideline says lithium still appears to have the most robust evidence base as a long-term treatment for bipolar disorder

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Bipolar disorder features as one of the top ten disabling disorders for working age adults. There are numerous risks including suicide, increased mortality and reduced social functioning associated with the disorder. Key to enabling recovery is preventing acute episodes from occurring, with each episode increasing the risk of future ones. Therefore ensuring long-term maintenance treatment [read the full story…]

Maintenance treatments for bipolar disorder: reducing the risk of manic, mixed or depressive relapse

Prescribing of medication for ADHD symptoms in young people with ASD is currently based on low quality evidence with a high risk of bias.

Many people with bipolar disorder have a range of therapies available to them nowadays, including mood stabilisers (or anticonvulsants), antipsychotics and various psychosocial interventions (including CBT, psychoeducation and family therapy). A research team from the University of Barcelona have published a meta-analysis that investigates the efficacy of drug maintenance treatments for bipolar disorder. They searched from [read the full story…]