This review estimating the nocebo response in dentistry from trials of analgesic treatment following third molar surgery included data from 50 RCTs. Adverse events (AEs) were roughly the same in placebo and active arms suggesting AEs may be attributed to the nocebo phenomenon.
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Colin Levey takes a look at a systematic review assessing the 10-year survival of titanium roughened surface, solid screw dental implants in adults. 4 RCTs and 14 prospective studies) were included traditional analysis and sensitivity analysis taking into account missing data was conducted providing a more conservative estimate of survival and a broader prediction interval.
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Simon Wessely responds to the huge amount of recent criticism that has surrounded the publication of a follow-up paper of the PACE trial into chronic fatigue syndrome. This extended blog presents the PACE trial and its main results, but also reminds us what makes a good RCT, as well as exploring how well PACE measures up.
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